Happy: High-throughput for microfluidics-enabled RLS

  • University of Luxembourg
  • From Luxembourg
  • Responsive
  • Innovative Products and Technologies

Summary of the technology

HAPPY is a microfluidic chip for high throughput drug screening in the area of longevity. Unlike all other methods, it is self-sufficient and does not require specialized equipment apart from the chip itself. It reduces manual workload by more than 92 %, and thus, enables pharmaceutical companies and drug developers to screen large collections of compounds for their lifespan extending properties. In addition, it enables the use of the lifespan properties of industrial production strains as optimization parameters.

University of Luxembourg

Details of the Technology Offer


Faster and reliable solution compared to existing RLS determination solutions. Single-use HAPPY-chip allows to perform high numbers of experiments in parallel and does not require expensive additional equipment or further microfluidic expertise. Thus, HAPPY chips can be used in every yeast lab in the world. The technique allows designing of stand-alone centrifugal devices, which could be operated by using commercial bench centrifuges.


The technique allows designing of stand-alone centrifugal devices, which could be operated by using commercial bench centrifuges and it’s applicable in the high-throughput screening of the lifespan extending properties of drugs (e.g. drug repurposing) and natural products (e.g. cosmetic supplements) but also for the optimization of industrial productions strains, as the productivity of a yeast cell depends on its aging properties.

Intellectual property status

Granted Patent

Patent number: PCT/EP2019/072988: Microfluidic systems for yeast aging analysis Priority date: 28-Aug-2018

Related Keywords

  • Electronics, IT and Telecomms
  • Electronics, Microelectronics
  • Industrial manufacturing, Material and Transport Technologies
  • Micro and Nanotechnology related to Electronics and Microelectronics
  • Consumer related
  • chips
  • microfluidics

About University of Luxembourg

The University of Luxembourg, founded in 2003, is multilingual, international and strongly focused on research. Its students and staff have chosen a modern institution with a personal atmosphere, close to the European institutions, international companies and the financial place.

Teaching, research and knowledge transfer at the highest international level: those are the goals that this university set from the start. With 270 professors, associate professors, assistant professors and senior lecturers, students from 130 different countries and lecturers originating from 20 different countries, the University offers a multicultural environment. Exchange agreements and research cooperations exist with 354 universities around the world.

About 6,783 students (Bachelor, Master, PhD/Doctorate, learning courses, vocational training and lifelong learning) can choose from over 60 degrees, offered by:
- The Faculty of Science, Technology and Medicine,
- The Faculty of Law, Economics and Finance,
- The Faculty of Humanities, Education and Social Sciences.

The central research priorities of the University of Luxembourg are:
- Materials Science
- Computer Science & ICT Security
- European and International Law
- Finance and Financial Innovation
- Education
- Digital and Contemporary History

as well as cross-disciplinary themes (details at https://www.uni.lu/research/focus_areas):
- Health and Systems Biomedicine
- Data Modelling and Simulation (formerly known as Computational Sciences)

University Rankings
- Among the top 250 universities in the Times Higher Education (THE) World University Rankings 2021.
- No. 3 worldwide in the THE “international outlook” Rankings 2021.
- No. 20 worldwide in the THE Young University Rankings 2021.

University of Luxembourg

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