BIOMARKER for prediction of recurrence in colorectal cancer patients

  • University of Luxembourg
  • From Luxembourg
  • Responsive
  • Research Services and Capabilities

Summary of the technology

Approximately 20% of colorectal cancer patients with stage II colorectal cancer experience relapse of the disease. Current clinical-pathologic stratification factors do not allow clear identification of these high-risk patients. The invention is a powerful prognostic biomarker in colorectal cancer, especially in early stages (stages I and II), which might help stratifying patients with stage II for adjuvant chemotherapy.

The invention provides a gene expression classifier that distinguishes patients with low or high risk of disease relapse in colorectal cancer and that might be used in the clinics to help clinicians identify high-risk patients and choose the most appropriate treatment for a given patient.

University of Luxembourg


• Cost efficient and easy-to-use solution for colon cancer management
• Identification of patients at high-risk in stage II MMR-P patients
• Prevent overtreatment with chemotherapy
• Improved prognostic accuracy


The invention has been implemented and tested in several public available databases containing clinical data on colorectal cancer patients.


Related Keywords

  • Applications for Health
  • Medicine, Human Health
  • Cytology, Cancerology, Oncology
  • Gene - DNA Therapy
  • Gene Expression, Proteom Research Technology
  • Medical Health related
  • Therapeutic
  • Oncology
  • biomarker
  • prognostic biomarker
  • Colorectal cancer
  • chemotherapy

About University of Luxembourg

The University of Luxembourg, founded in 2003, is multilingual, international and strongly focused on research. Its students and staff have chosen a modern institution with a personal atmosphere, close to the European institutions, international companies and the financial place.

Teaching, research and knowledge transfer at the highest international level: those are the goals that this university set from the start. With 270 professors, associate professors, assistant professors and senior lecturers, students from 130 different countries and lecturers originating from 20 different countries, the University offers a multicultural environment. Exchange agreements and research cooperations exist with 354 universities around the world.

About 6,783 students (Bachelor, Master, PhD/Doctorate, learning courses, vocational training and lifelong learning) can choose from over 60 degrees, offered by:
- The Faculty of Science, Technology and Medicine,
- The Faculty of Law, Economics and Finance,
- The Faculty of Humanities, Education and Social Sciences.

The central research priorities of the University of Luxembourg are:
- Materials Science
- Computer Science & ICT Security
- European and International Law
- Finance and Financial Innovation
- Education
- Digital and Contemporary History

as well as cross-disciplinary themes (details at
- Health and Systems Biomedicine
- Data Modelling and Simulation (formerly known as Computational Sciences)

University Rankings
- Among the top 250 universities in the Times Higher Education (THE) World University Rankings 2021.
- No. 3 worldwide in the THE “international outlook” Rankings 2021.
- No. 20 worldwide in the THE Young University Rankings 2021.

University of Luxembourg

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