RODENT PLATFORM - Luxembourg Centre for Systems Biomedicine

  • University of Luxembourg
  • From Luxembourg
  • Responsive
  • Research Services and Capabilities

Summary of the technology

The new University rodent facility is a shared resource of the Luxembourg Centre for Systems Biomedicine (LCSB) and the Life Science Research Unit (LSRU) and has been established to assist researchers in the development and analysis of various in vivo models including germ-free animals.

University of Luxembourg

OUR FACILITY

The facility offers space for 1200 mouse cages and 300 rat cages and consists of two breeding rooms, three surgery rooms and three behavioural rooms. Bedding, water and cages are sterilised by autoclaving and the feed is irradiated. A comprehensive health surveillance system is in place and microbiological and environmental parameters are constantly monitored to ensure the breeding of healthy rodents. Our animals are hosted in a modern facility, ensuring the highest animal welfare possible by a culture of care. All personnel is experienced and regularly trained/certified by mandatory courses following the guidelines developed by the EU for a common education and training framework and recommendations of the FELASA (Federation of European Laboratory Science Experimentation). A designated veterinarian inspects regularly the animals and advises on a wide range of animal welfare topic.

The specific and opportunistic pathogen free (SOPF) breeding area has the capacity to house about 600 individually ventilated mouse cages and more than 100 different mouse lines can be maintained and bred there. The specific pathogen free (SPF) experimental area has the capacity to house 600 mouse and 300 rat cages dedicated to experimental studies on transgenic rodents, use of different viral vectors and monitoring of xenograft models.

SERVICES OFFERED

  • Animal housing & Husbandry
  • SOPF breeding area and SPF experimental area
  • Germ-free unit
  • Humanized mice
  • Transgenesis in the mouse via CRISPR-Cas9 system

The facility also offers the possibility of running a broad number of experimental procedures, including behavioural tests, surgical procedures, humanised mice models and monitoring of the mice through non-invasive imaging technologies (bioluminescence imaging system).

Attached documents

Related Keywords

  • Physical Sciences and Exact Sciences
  • Biological Sciences
  • Industrial Biotechnology
  • surgical procedures
  • rodents
  • genome research
  • human mice models
  • monitoring equipment

About University of Luxembourg

The University of Luxembourg, founded in 2003, is multilingual, international and strongly focused on research. Its students and staff have chosen a modern institution with a personal atmosphere, close to the European institutions, international companies and the financial place.

Teaching, research and knowledge transfer at the highest international level: those are the goals that this university set from the start. With 270 professors, associate professors, assistant professors and senior lecturers, students from 130 different countries and lecturers originating from 20 different countries, the University offers a multicultural environment. Exchange agreements and research cooperations exist with 354 universities around the world.

About 6,783 students (Bachelor, Master, PhD/Doctorate, learning courses, vocational training and lifelong learning) can choose from over 60 degrees, offered by:
- The Faculty of Science, Technology and Medicine,
- The Faculty of Law, Economics and Finance,
- The Faculty of Humanities, Education and Social Sciences.

The central research priorities of the University of Luxembourg are:
- Materials Science
- Computer Science & ICT Security
- European and International Law
- Finance and Financial Innovation
- Education
- Digital and Contemporary History

as well as cross-disciplinary themes (details at https://www.uni.lu/research/focus_areas):
- Health and Systems Biomedicine
- Data Modelling and Simulation (formerly known as Computational Sciences)

University Rankings
- Among the top 250 universities in the Times Higher Education (THE) World University Rankings 2021.
- No. 3 worldwide in the THE “international outlook” Rankings 2021.
- No. 20 worldwide in the THE Young University Rankings 2021.
https://wwwen.uni.lu/university/about_the_university/rankings_accreditations

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