We offer a new software for your fermentation. This is the analytical software based on new theory, which is described in the article in the attached file. This is a promo video to the software:
English: " rel="nofollow" target="_blank">https://www.youtube.com/watch?v=gEAZXP8R2yI
Russian: " rel="nofollow" target="_blank">https://www.youtube.com/watch?v=uMw0Q3VI_wY
You could find more details here: http://fermentertool.com/en/
One of the main provisions in our experience could be formulated as: any biosynthesis involves in fact two processes - "positive " and " negative ". We assume that metabolites are synthesized only by proliferating cells. Non-proliferating cells, as a rule, destroy these products. Therefore, the signs of the constants for metabolite synthesis and degradation are opposite. The same should be stated for any substrates utilized for cell construction. All these can give a "separation" of these two processes and make recommendations to increase economic efficiency.
Our mathematical model gives to physiological similarity of cultures in different volumes, as a criterion for different scale up procedures. This similarity is equal (or close) to ratio between of the dividing cells and non-dividing cells numbers for two (three, etc.) various volumes, which will be compared between each other: 10 liters, 1 cubic meter, etc. This indicator is marked with "R" in our articles.
Our software will help you solve the following tasks:
a. modeling of your fermentation process data;
b. predicting of the optimal processes;
c. detecting of the limiting substrates according to 'a' and then to do all the calculations to achieve forecasts 'b'.
This is an unique software. Now I'm sending some materials and test calculations for different biomass, products, substrates (including C, N, P, Mg, S). The software is appropriate for calculations of all S-shaped curves for all batch processes.
You could be registered here: http://fermentertool.com/tool/
Please, don't forget to confirm your registration when the corresponding letter will be delivered to you. (This letter may be in the "Spam", so you need to check all the folders in your e-mail address.) For testing, we offer 1 free attempts for calculations (only biomass or biomass+ (P+S)- up to 10 for both of each).
If you will want more free attempts, it can be discussed. Please, bear in mind that the deadline to submit our reports on our calculations in the test period is limited from 1-2 hours to 2 days, because some automatic functions are disabled.
Here's the address for PayPal payments: firstname.lastname@example.org
The price is US$ 40 for 1 calculation. (Payment for use of the time account will be introduced after the end of the test period.)
1) The data for the biomass should be as S- shaped curves (!)
2) The software minimal quantity of dots for the Biomass,X=f(t), should be equal no less than 8 (~4 dots for Exponential Phase of the growth curve and ~4 dots for Slow Phase.)
3) The stationary growth phase has a little significance for our software. If you have doubts about your data, please, check them through charting in the Excel programm.
We hope for mutually beneficial cooperation and we would be grateful if you keep this information confidential until we are done with the final release of software.
Sergey Klykov, PhD
Short description of how tool can be used
Dear colleague Bhattacharya,Sourish, I would like to help you when using our software for fermentation. 1) Enter your login and password. 2) Select the button, which is necessary for calculations. This can be "Calculations for biomass" or "Calculations of biomass and product"; the last button will do the calculations also for substrates. You should remember that our software can work only with concentrations data. For biomass: g/l, billions of cells/ml, a.u./ml. 3) Enter into the left column the values of the time of cultivation, into the right one the values of biomass. If you have done the selection buttons Calculations of biomass and product", you can enter the values of products and substrates after biomass in the field, which lies on right from the biomass column. For one of biomass you can make putting up to 10 values of different substrates (e.g., sources of carbon, nitrogen, phosphorus, magnesium, etc.) and up to 10 different values of products (e.g., penicillin and/or penicillin biosynthesis related products). 4) Push "Send" button, when the procedure of entering of your data was completed; and you will be waiting for the Report in your Inbox for your emails during from 1-2 hours to 1-2 days, because the software can not be included at any time of the day. Please note: 1) The data for the biomass should be as S- shaped curves (!) 2) The software minimal quantity of dots for the Biomass,X=f(t), should be equal no less than 8 , (~4 dots for Exponential Phase of the growth curve and ~4 dots for Slow Phase.) 3) The stationary growth phase has a little significance for our software. If you have doubts about your data, please, check them through charting in the Excel programm.