A NEW DRUG FOR THE PREVENTION AND TREATMENT OF HERPES SIMPLEX VIRUS (HSV-1)

Summary of the technology

The subject of the new invention is new drug developed by researchers of the Jagiellonian University is intended for prevention and treatment of herpes simplex virus (HSV-1)– application in biotechnology & medicine.

Centre Technology Transfer CITTRU

New and innovative aspects

 

Herpes simplex virus 1 (HSV-1), is one of the most commonly encountered pathogens in humans. The most recent statistics indicate that approximately 50-90% of the world population is HSV-1 seropositive. The most common primary infections are cold sores occurring mainly on the face (especially the skin, tongue and lips). However, infection with HSV-1 may also lead to severe diseases such as inflammation of the eye or encephalitis. These diseases are characterized by severe course and may cause permanent adverse health effects (e.g. blindness), and even death.

 

Currently, there are several antiviral drugs, which are active against pathogens belonging to the Herpesviridae family. These drugs reduce the frequency and severity of relapses and also alleviate bothersome symptoms during the primary infection. Although they are usually only effective for the initial infection, they do not eliminate a virus in a latent state and thus do not protect a person before re-emergence of symptoms. There has also been increasing emergence of drug resistant viral strains. Thus, there is a need to find a new approach to developing effective treatment of HSV-1 infection.

 

The new invention of the Jagiellonian University, which is the subject of the proposed offer, discloses a new drug for treatment of herpes simplex virus (HSV-1) infection.

 

Main advantages of its use

 

The main advantages of the offered drug are:

 

  • confirmed ability to efficient bind of herpes simplex virus (HSV-1) and inhibit its replication in vitro,
  • low-toxicity of the drug in vitro,
  • the possibility to apply as an ointment or solution administrated either topically to the skin or eye, orally, intraperitoneally or intravenously.

Specifications

 

The goal of the invention was to develop a substance inhibiting replication of herpes simplex virus (HSV-1), which would find application in prevention or therapy of infections caused by this virus in human organisms. Unexpectedly the researchers at the Jagiellonian University developed a substance as a medicine which may find the application thereof.

 

Applications

 

  • A new drug developed by researchers of the Jagiellonian University is intended for prevention and treatment of herpes simplex virus (HSV-1) – application in biotechnology & medicine.

Intellectual property status

 

A new drug for prevention and treatment of herpes simplex virus (HSV-1), is the subject of patent application in Poland (PCT patent application – April 2017).

 

Current development status

 

Working prototype or samples ready for testing.

 

Desired business relationship

 

- commercial agreement

 

- licence aggreement

 

- technical cooperation – further development

 

- technical cooperation – adaptation to specific needs

 

EN328_JU

Intellectual property status

Related Keywords

  • Pharmaceutical Products / Drugs
  • Virus, Virology / Antibiotics / Bacteriology
  • Biochemistry / Biophysics Technology
  • Microbiology Technology
  • Care, Hygiene, Beauty, Cosmetics
  • Therapeutic
  • Pharmaceuticals/fine chemicals
  • Consumer Products
  • Drug
  • medicine
  • Herpes Simplex Virus
  • dextran
  • hsv-1
  • cold sores

About Centre Technology Transfer CITTRU

Jagiellonian University, founded 1364, is the oldest university in Poland and one of the oldest worldwide. The research and teaching activities are conducted at 15 faculties, including the Medical College (Collegium Medicum). Over 3,700 researchers work at the university and the total number of students is about 50,000.

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