Novel markers for the identification and isolation of stem and progenitor cells

Summary of the technology

A series of novel markers: (1) chromatin remodeling protein factor termed (CHD9/CReMM), (2) A cell adhesion protein termed (SVEP1), (3) A kinesin protein termed (MS-KIF18A), (4) RNA processing factor (SRRF/hNRNP-L) have been developed as novel markers for the identification and isolation of stem and progenitor cells.
Project ID : 10-2007-104

Details of the Technology Offer

Technology
A series of novel markers: (1) chromatin remodeling protein factor termed (CHD9/CReMM), (2) A cell adhesion protein termed (SVEP1), (3) A kinesin protein termed (MS-KIF18A), (4) RNA processing factor (SRRF/hNRNP-L) have been developed as novel markers for the identification and isolation of stem and progenitor cell.

Potential Applications

  • Identification of stem cells from skeletal muscle, mesenchymal cells and adipose derived stem cells
  • Isolation and enrichment of specific sub populations of stem cells and progenitors cells
  • Modulation of expression for controlled differentiation of MSCs
  • QC for cell differentiation

Stage of development
Antibodies have been raised to monitor protein expression in in vitro and in vivo studies

Patents
7,829,296; 7,919,602
US pending


Project manager

Elisha Natan
Director BD

Project researchers

Dafna Benayahu
T.A.U Tel Aviv University, Medicine-Sackler Faculty
Cell and Developmental Biology

Related Keywords

  • Medicine, Human Health
  • Medical Technology / Biomedical Engineering
  • Biology / Biotechnology
  • Cellular and Molecular Biology Technology
  • Microbiology Technology
  • Bioinformatics Technology
  • Micro- and Nanotechnology related to Biological sciences
  • Microbiology Market
  • Micro- and Nanotechnology related to Biological sciences
  • Biochemistry / Biophysics Market
  • Stem cells and biobanks
  • Cellular and Molecular Biology Market
  • Bioinformatics Market
  • Therapeutic
  • Clinical Medicine
  • Pharmaceutical Indications
  • Life Sciences and Biotechnology
  • Stem Cells
  • Cell therapy

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Ramot is Tel Aviv University's (TAU) technology transfer company and its liaison to industry, bringing promising scientific discoveries made at the university to industry's attention. The company provides the legal and commercial frameworks for inventions made by TAU faculty, students and researchers, protecting discoveries with patents and working jointly with industry to bring scientific innovations to the market.

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