Metabolic Biomarkers for Early Detection of Memory Impairment Risk

Summary of the technology

This invention provides a method for determining a subject's risk of memory impairment by analyzing plasma metabolite profiles. It involves comparing the subject's metabolite concentrations to normal values at multiple time points. Changes in specific metabolite levels indicate an increased risk of memory impairment, allowing for early intervention and treatment. This non-invasive blood test offers a potential screening tool for preclinical stages of cognitive decline.

Georgetown University

Details of the Technology Offer

BACKGROUND

Early detection of Alzheimer's disease and mild cognitive impairment is crucial for effective intervention, but current diagnostic methods are invasive, expensive, or limited in widespread applicability. This invention addresses the need for a simple, cost-effective blood-based biomarker test to identify individuals at risk of memory impairment before clinical symptoms appear.

Benefit

  • Non-invasive blood test for assessing memory impairment risk
  • Potential for earlier detection of cognitive decline compared to current methods
  • More cost-effective and accessible than neuroimaging or CSF analysis
  • Allows for monitoring of disease progression over time
  • May provide insights into underlying mechanisms of cognitive decline

Market Application

  • Potential use in primary care settings for routine cognitive health screening
  • Possible application in clinical trials for patient selection and monitoring
  • Can be implemented in memory clinics for early diagnosis and treatment planning
  • Suitable for integration into personalized medicine approaches for cognitive health

Intellectual property status

- Granted Patent

Patent number : Patent No. 10,900,980

Where : USA

- Granted Patent

Patent number : Patent No. 11,808,774

Where : USA

Related Keywords

  • Medical Research
  • early detection
  • cognitive decline
  • biomarkers
  • alzheimer disease

About Georgetown University

Our mission is to advance GU’s innovations through strategic alliances and new venture creation, to facilitate the translation of research breakthroughs into tangible solutions, and to cultivate a dynamic and inclusive environment for entrepreneurship. We advance this mission in support of the GU community and for the benefit of society.

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