Greenpharm – vaccine production in tobacco leaf
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Technology Offer
Greenpharm – vaccine production in tobacco leaf
- CSIR
- From South Africa
- Responsive
- Innovative Products and Technologies
Summary of the technology
GreenPharm offers a new, scalable manufacturing technology that makes use of transient expression for rapid expression of product.
Applications
Post-exposure prophylaxis against rabies
Technology Field
Biosciences
Business Opportunity
Seeking investment for pre-clinical and clinical trials
Technology Description
GreenPharm has developed a monoclonal antibody (mAb)-based post-exposure prophylaxis against rabies, which is an acute viral disease transmitted through the bite of rabid animals. The unique cocktail of two potent mAB’s, known as Rabivir™, will replace the current post-exposure treatment which uses human or equine rabies immune globulin. GreenPharm offers a new, scalable manufacturing technology that makes use of transient expression for rapid expression of product. This proprietary manufacturing platform will substantially lower the manufacturing cost and this is likely to allow RabiVir™ to be a better priced product for the combat of rabies in developing countries.
Benefits & Advantages
Safer – mammalian pathogen-free Greater efficacy Reliable supply – technology scalable to suit demand Cost effective
Inventors
Sonia Rech, Stoyan Stoychev, Tsepo Tsekoa,Therese Stark, Erek Chakauya, Rachel Chikwamba, Fanie Marais
Related Keywords
About CSIR
The Council for Scientific and Industrial Research, commonly known as the CSIR, is a world-class African research and development organisation established through an Act of Parliament in 1945. The CSIR undertakes directed, multidisciplinary research and technological innovation that contributes to the improved quality of life of South Africans.
The CSIR’s shareholder is the South African Parliament, held in proxy by the Minister of Higher Education, Science and Innovation.
CSIR vision
We are accelerators of socio-economic prosperity in South Africa through leading innovation.
CSIR mission
Collaboratively innovating and localising technologies while providing knowledge solutions for the inclusive and sustainable advancement of industry and society.
CSIR values
CSIR values statement:
Our beliefs, principles and the impact we wish to make to improve the quality of life of South Africans are EPIC. Team CSIR pursues Excellence, celebrates People, personifies Integrity, and welcomes Collaboration.
Our mandate
“The objects of the CSIR are, through directed and particularly multi-disciplinary research and technological innovation, to foster, in the national interest and in fields which in its opinion should receive preference, industrial and scientific development, either by itself or in co-operation with principals from the private or public sectors, and thereby to contribute to the improvement of the quality of life of the people of the Republic, and to perform any other functions that may be assigned to the CSIR by or under this Act.”
(Scientific Research Council Act 46 of 1988, amended by Act 71 of 1990)
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