RAMOT at Tel Aviv University Ltd.

Enhancement of Durability, Sensitivity and Selectivity of Environmental Sensors & BioSensors by Peptide Nanotubes

Posted by RAMOT at Tel Aviv University Ltd.Responsive · Innovative Products and Technologies · Israel

Summary of the technology

A Peptide NanoForest, is a dense array of self assembling organic nanotubes, capable of enhancing sensitivity and selectivity parameters of amperometric electrode high-performance sensors.
The patented Diphenylalanine (FF) aromatic dipeptide nanotubes are formed under mild conditions from inexpensive building blocks. These bioinspired materials have a unique mechanical strength. They have a high Young’s modulus of about 20–30 GPa. In addition, the inherent biocompatibility of the structures along with the options of their chemical and biological modifications, extraordinary thermal stability, and organic solvent stability, lead to a novel class of nanostructures for sensing applications.
The vertical arrangement of the peptide nanotubes enable the deposition of a larger number of nanotubes on the same surface, resulting in a remarkable surface area increase. FF peptide-nanotube-based sensors are benchmarked to CNT-based sensor, and clearly demonstrate the enhancement effect.
Project ID : 3-2011-149

RAMOT at Tel Aviv University Ltd.

The Technology

A Peptide NanoForest, is a dense array of self assembling organic nanotubes, capable of enhancing sensitivity and selectivity parameters of amperometric electrode high-performance sensors.
The patented Diphenylalanine (FF) aromatic dipeptide nanotubes are formed under mild conditions from inexpensive building blocks. These bioinspired materials have a unique mechanical strength. They have a high Young’s modulus of about 20–30 GPa. In addition, the inherent biocompatibility of the structures along with the options of their chemical and biological modifications, extraordinary thermal stability, and organic solvent stability, lead to a novel class of nanostructures for sensing applications.

Potential Application

The vertical arrangement of the peptide nanotubes enable the deposition of a larger number of nanotubes on the same surface, resulting in a remarkable surface area increase. FF peptide-nanotube-based sensors are benchmarked to CNT-based sensor, and clearly demonstrate the enhancement and sensitivity effect.

Patents

Three granted patents and three patent applications in various stages.

Supporting Publications

Characterization of Peptide-Nanostructure-Modified Electrodes and Their Application for Ultrasensitive Environmental Monitoring, E. Gazit & J. Rishpon et al, Small, 2010, 6(7):825.

Novel Electrochemical Biosensing Platform Using Self-Assembled Peptide Nanotubes, E. Gazit & J. Rishpon et al, Nano Letters, 2005, 5(1):183.

Peptide Nanotube-Modified Electrodes for Enzyme-Biosensor Applications, E. Gazit & J. Rishpon et al, Analytical Chemistry, 2005, 77(16):5155.

Project manager

Rona Samler
VP, BD Physical Science, Medical Device, Chemistry

Project researchers

Ehud Gazit
T.A.U Tel Aviv University, Life Sciences
Molecular Microbiology-Biotechnology

Related keywords

  • Micro- and Nanotechnology
  • Safety
  • Environment
  • Water Management
  • Waste Management
  • Nanomaterials
  • Micro- and Nanotechnology related to energy
  • Micro- and Nanotechnology related to agriculture and marine resources
  • Environmental and Biometrics Sensors, Actuators
  • Sensors for cars and transport
  • Biosensor
  • Sensors & Wireless products
  • Sensor Technology related to measurements
  • Micro- and Nanotechnology related to Biological sciences
  • Chemicals and Materials
  • Pollution and Recycling Related
  • Oil and Gas Exploration and Production
  • Alternative Energy
  • Energy Storage
  • Other Industrial Products (not elsewhere classified)
  • Industrial measurement and sensing equipment
  • Environmental and Cleantech
  • sensors
  • sensors
  • Environmental and Cleantech
  • Water
  • sensors
  • Nanotechnology
  • energy
  • Water & the Environment
  • sensors
  • Nanotechnology
  • energy
  • Water & the Environment
  • Nanotechnology

About RAMOT at Tel Aviv University Ltd.

Technology Transfer Office from Israel

Ramot is Tel Aviv University's (TAU) technology transfer company and its liaison to industry, bringing promising scientific discoveries made at

Send your request

By clicking "Send your request" you are signing up and accepting our Terms of Service and Privacy policy

Technology Offers on Innoget are directly posted and managed by its members as well as evaluation of requests for information. Innoget is the trusted open innovation and science network aimed at directly connect industry needs with professionals online.