Fluorescence Assisted Genome Editing

  • University of Luxembourg
  • From Luxembourg
  • Responsive
  • Knowhow and Research output

Summary of the technology

Efficient method to derive genome edited populations by the use of fluorescent markers. The Fluorescence Assisted Genome Editing technique allows deriving correctly edited clones with precision genetic modifications. Produced cells are free from non-edited, random integrations and on-target allele NHEJ-containing populations.

University of Luxembourg



  • Faster than conventional methods. Screening of positive clones can be performed using FACS analysis instead of PCR.
  • Multiple mutations can be generated in high throughput manner creating single nucleotide variants collections.


  • Genetic variants can be deposited in human induced pluripotent stem cells, enabling the generation of any cell type of interest. E.g. brain, muscle or pancreas.
  • Genetic correction allows patients suffering from genetic disorders to obtain healthy cells for tissue therapy.


LU92964 – Means and methods for selecting transformed cells


  • Enable the derivation of isogenic libraries containing mutations relevant to any disease.
  • Isogenic cell libraries permit high-throughput chemical compound screening.

Attached documents

Related Keywords

  • Biological Sciences
  • Medicine, Human Health
  • Clinical Research, Trials
  • Genetic Engineering / Molecular Biology
  • Stem cells and biobanks
  • Cellular and Molecular Biology Market
  • Gene Expression, Proteom Research Market
  • fluorescent markers

About University of Luxembourg

The University of Luxembourg, founded in 2003, is multilingual, international and strongly focused on research. Its students and staff have chosen a modern institution with a personal atmosphere, close to the European institutions, international companies and the financial place.

Teaching, research and knowledge transfer at the highest international level: those are the goals that this university set from the start. With 270 professors, associate professors, assistant professors and senior lecturers, students from 130 different countries and lecturers originating from 20 different countries, the University offers a multicultural environment. Exchange agreements and research cooperations exist with 354 universities around the world.

About 6,783 students (Bachelor, Master, PhD/Doctorate, learning courses, vocational training and lifelong learning) can choose from over 60 degrees, offered by:
- The Faculty of Science, Technology and Medicine,
- The Faculty of Law, Economics and Finance,
- The Faculty of Humanities, Education and Social Sciences.

The central research priorities of the University of Luxembourg are:
- Materials Science
- Computer Science & ICT Security
- European and International Law
- Finance and Financial Innovation
- Education
- Digital and Contemporary History

as well as cross-disciplinary themes (details at https://www.uni.lu/research/focus_areas):
- Health and Systems Biomedicine
- Data Modelling and Simulation (formerly known as Computational Sciences)

University Rankings
- Among the top 250 universities in the Times Higher Education (THE) World University Rankings 2021.
- No. 3 worldwide in the THE “international outlook” Rankings 2021.
- No. 20 worldwide in the THE Young University Rankings 2021.

University of Luxembourg

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