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Innovation Intermediary from Russian Federation · Moscow region

We are a team of programmers/mathematicians , which deals with calculations of microbial processes in order to improve their effectiveness. The program is designed for engineers and scientists in the microbiological industry and R&D areas for planning, analysis and control of the fermentations, as well as for undergraduate and graduate students who are trained in the microbiological field. An Integrated Mathematical Model of Development (IMMD) is the basis of these calculations. The IMMD have 3 basic paradigms. Russian Federation Patent # 2228352: For biomass: dnXdiv/d((Xst))n= {(K/A2) ∗ [(−1)(n−1)]*n!} / [(Xst)(n+1)]− C, (1); For product(substrates): dP(or − S)/dτ = kdiv(for P and-S)Xdiv + kst(for P and -S)Xst, (2). Please, see http://iopscience.iop.org/1758-5090/3/4/045006 For each separate phase we must have separate equations. The physiological processes occurring in proliferating and stable (non-proliferating) cells differ greatly and are diametrically opposed. We assume that metabolites are synthesized only by proliferating cells. Nonproliferating cells, as a rule, destroy these products. Therefore, signs of the constants for metabolite synthesis and degradation are opposite. The same should be stated for substrates utilized for cell construction. Our equations describe all the known diversity of the processes with S-like growth curves and changes in the concentrations of substances in closed systems, which is an entirely new and previously unknown fact. It is known that a physical law means a generalization of a numerical relationship between the objects of the real physical world that is running under specified conditions for the class of the objects and does not follow from any of the previously discovered laws. There is no reason not to admit the two described equations for the GIP as laws for GIP. The data obtained were used for the selection of techniques to increase the protein expression by genetically modified microorganisms. Also, this software version allows you to calculate the energy indicators of the population: a - is a trophic factor; m - is specific an energy consumption for maintenance of life; f - is a consumption of an energy substrate for building of cells bodies.

Mid-Market Company from United States

As a global Contract Research Organization (CRO), headquartered in New York, USA, Alfa Chemistry has served the pharmaceutical and biotechnology industries for eight years. Today, Alfa Chemistry employs more than 200 full time staff, of which approximate 80 are Ph.D. and M.S. chemists, specialized in synthetic chemistry, process optimization, and research. Alfa Chemistry offers an extensive catalog of building blocks, reagents, catalysts, reference materials, and research chemicals in a wide range of applications. We also provide analytical services and laboratory services to our customers. Products listed on our website are either in stock or can be resynthesized within a reasonable time frame. In stock products can be shipped out within 3-5 business days upon receipt of customers' purchase order. You may search for our products through the search bar on our website. If the products you look for are not in our catalog we would be pleased to offer our custom synthesis service. We make the custom synthesis process more efficient and cost effective while maintaining the highest standards of quality and reliability. Our trained chemists work on custom projects designed specifically for the needs of each client. More than 300 different organizations from at least 40 countries worldwide have used Alfa Chemistry's products and services since its inception. A large part of Alfa Chemistry's customers are pharmaceutical and biotechnology companies, including Pfizer, Novartis, Merck & Co., Johnson & Johnson, AstraZeneca, and Bayer. Alfa Chemistry is also a preferred partner for many universities and non-profit institutes.