OctoCells develops CellSpace HA™, a proprietary 3D bioactive hyaluronic acid matrix that turns standard culture vessels into ready-to-use bioproduction microfactories , no new equipment, no protocol change, same incubator.
Unlike inert microcarriers (dextran, polystyrene) that require collagen or Matrigel coating, CellSpace HA is intrinsically bioactive: cells recognize and colonize it natively, in a true 3D volume rather than a flat 2D surface. The matrix supports a broad range of cell types, including non-adherent cells, and applications spanning monoclonal antibodies, extracellular vesicles, lentiviral vectors, recombinant proteins, and physiologically relevant 3D disease models.
Results independently validated with Rouen University Hospital, CNRS and INSERM: ≥12× monoclonal antibody yield vs. standard 2D culture, +54% extracellular vesicle production, −80% cost per unit produced (vessel + medium + labor), and active cultures maintained beyond 29 days versus a typical plateau at day 18 in 2D. The technology is protected by 3 patents filed plus 1 in the pipeline, and has been validated in partnership with Dassault Systèmes on OctoSim™, an AI-powered digital twin for bioproduction.
OctoCells is a French deeptech biotech based in Rouen, currently engaging with CDMOs, biopharma manufacturers, and academic/clinical partners to scale adoption of CellSpace HA across bioproduction and 3D modeling applications.
We are actively seeking industrial partners, co-development opportunities, and technology providers (e.g., animal-free growth factors, specialty proteins) to complement our platform and accelerate deployment across new modalities and markets.

We are currently seeking best-in-class collaboration partners for our publications listed in the tab Opportunities. We want to invite you to cooperate with us, so please repond to any of the opportunities by submitting one or more proposals. Our team will directly evaluate them and get back to you with a response. Please provide as much detailed non-confidential information as possible to facilitate the engagement process.