Know-how and Research output from top scientists and innovators, including know-how submitted for an abandoned patent and research for which no patent was filled
Yissum - Research Development Company of the Hebrew University posted this:VitaLunga: Novel Oral Drug-Candidate to Prevent Age-Related Degenerative DiseasesBriefly, Some of the degenerative diseases associated with aging (such as Parkinson's Disease, Alzheimer's Dis., Congestive heart failure and more) are caused by decrease in the removal of defective mitochondria; a quality-control process known as mitophagy. The current technology/concept will enable the restoration of mitophagy efficiency, thereby prevent the evolvement of age-related degenerative diseases. As such, it can be used as a treatment; which is a major medically unmet need. The concept: Spermidine (Spd) is a natural polyamine regulating important and diverse physiological processes such as cell growth, cell proliferation, and programmed cell death. The concentration of Spd is decreasing with age in mammals hence it was suggested to adapt a dietary supplementation of Spd to compensate for the natural loss with age and thus support healthy aging. However, the usefulness of Spd as a drug is limited because it can be degraded by gut-associated bacteria and its excessive accumulation inside mammalian cells can result in toxic product formation. And this is exactly where the 6443 (Novel small molecules that facilitate mitophagy ) kicks in. the team suggests to synthesis parallel molecules that mimic this MOA or at least by applying them you receive the same effect of restoration. As of today, several applications have been submitted lately by the group in order to demonstrate the superiority of healthspan of these novel set of stable polyamine-like compounds (compared to native Spd),. Current status: the research was funded by the HUJI funds (קרן המחקר לגימלאים ) resulting with a preliminary findings as specified below. In addition, pre-proposal already sent to the Israeli Ministry of Science and similar. One will be soon submitted to ERC PoC Grant. Based on Ariela, the team would like to have FTO and mainly being able to speak this notion. Conclusion: Following Tami’s email, a conversation I had with Ariela and the materials handed by the researchers it is not possible to review the technology/matured concept further due to lack of information/data. The studied as conducted so far were based on in vivo exp., with Caenorhabditis elegans nematode, which is extensively used as a model organism. The goal was to explore the potency of five compounds as mitophagy-inducers using imaging experiments. The researchers identified successfully two compounds that induced mitophagy (MAC1* and MAC4*) where MAC4 was superior to MAC1 and both Project ID : 6-2018-4576
Yissum - Research Development Company of the Hebrew University posted this:Copper Ink as Seed Layer for 3D Copper PlatingCopper Ink as Seed Layer for 3D Copper Plating Project ID : 31-2018-4540
Universidad de Alcalá-OTRI posted this:Diagnosis and solutions to improve mortuary services in cemeteries.A research group of the Department of Legal Sciences of the University of Alcalá offers a consultancy service for the diagnosis and management of mortuary services in cemeteries, based on the study and application of the right to religious freedom in these spaces. The group seeks to reach commercial agreements with technical assistance or technical cooperation, with town halls, public and private cemeteries as well as funeral companies.
Technology Transfer Office
Universidade de Santiago de Compostela posted this:GRAPHENE NANOSTRUCTURES: Bottom-Up Approacha) SUBSTITUTED POLYAROMATICS to be used as building blocks in the preparation of graphene nanoribbons (GNRs) of graphene quantum dots (GQDs). b) WELL-DEFINED NANOSIZED GRAPHENES obtained by solution chemistry: homogeneous, different sizes, peripheries and substitution.
IVAN RODRIGUEZ ROSELLO posted this:
Licensing Manager at UNIVERSIDAD DE ALICANTE
private researcher posted this:EmDrive two is new version of this machine, which provides huge thrust, big enough for satelites and flying vehicles.I am offering my know-how to someone interested in EmDrive device, which can be useful for satelites and flying vehicles, such as drones and similar. My version of EmDrive is mechanical, it does not use microwaves, thrust is huge and it can not be compared with original EmDrive from England. The principle of work is simple, device is cheap and runs on electromotor.
Miguel Menendez posted this:
Professor / PhD. at Universidad de Zaragoza
University of Huelva posted this:Power supply system controlled from internet for devices connected to a lanNowadays there are devices that allow the control of devices connected to a network from the own network. The classical method to access them from a different network is the redirection of the corresponding TCP or UDP connections to local networks from the border router. The redirection requires a high level of expertise in communications to be performed. Another strategy that is often used is the creation of VPN (virtual private network). This technique allows the control of access but does not allow connections to be discriminated or the management of power supply. The proposed system allows you to control the person and the moment to access as well as the free access. The modification of these constrains can be performed in the course of an access session. In addition, the system allows the control of power supply of the device you want access to. The interface is very friendly and does not require continuous changes in the configuration of the router. The system has a local database access control and validation can be delegated to other servers using protocol validation like LDAP, IMAP, POP3, etc.
Juan Casado posted this:
R&D Manager at UAB
Oleksandr Malyuskin posted this:
CEO at Acorn Microwave Solutions
Universidad de Alcalá-OTRI posted this:New free online course in Translation and Interpreting in Public ServicesThe FITISPos and FITISPos e-learning groups of the University of Alcalá present an introductory MOOC course for the training of bilingual people who act as translators and interpreters in public services or in situations in which the figure of these professionals is necessary. The online course is entitled: "Get Started in Translation and Interpreting in Public Services". The main objective of this course is to work on issues related to the communication process between foreign users who are not familiar with the Spanish language and the public or private institutions that provide services to society. The course is also focused on describing and practicing the functions of the translators and interpreters who work in these areas and showing how to get to work within this booming sector. The research groups FITISPos and FITISPos -ELearning seek to reach commercial agreements with technical assistance or technical cooperation agreements with public services and public institutions (courts, police stations, hospitals, schools, town halls, etc.) or private institutions (NGOs, associations of entrepreneurs with international interests or foreign employees, banks, tourist offices, etc.).
University of Huelva posted this:New procedure for the purification of water contaminated by metals and the respective systemsThe invention solves the problems of inefficiency which usually shows the conventional passive treatment systems. The reactive fills developed for the removal of inorganic contaminants historically have focused on removing low concentrations of these (typical features of coal mining), however when these fillers are faced to high concentrations of metals (sulfur mining, uranium, industrial water waste…) quickly clogging and loss of reactivity occurs. The present invention allows the removal of metals without clogging and/or loss of reactivity. This is achieved by the use of a coarse inert material with high surface mixed with a fine-grained reactive material, so that the surface of the inert material is breaded with reactive material. Coarse fragments of inert material act as a frame, providing large pores that reduces clogging by precipitates. The small particle size of the reactive material provides a large surface area that increases its reactivity.
University of Huelva posted this:New power generation electric systemThe proposed system is characterized by the following aspects which make it unique: 1- The system is built from a number of PEM fuel cells, supplied by al least one hydrogen source. Each module include a monitoring and control subsystem, so it is possible to activate/deactivate module induividually. 2- Each module can supply a different power value. 3- The monitoring and control subsystem receives electrical signal from each modules like stack voltage, stack current and cell voltage. 4- The monitoring and control system has two levels: the first level aims to control each module (local control) and the second level is responsible for coordinate local controller. 5- The monitoring and control system is on-line accessible. 6- The control and monitoring system distributes homogeneously the operating hours between the modules when the power demand is lower than the maximum power. 7- Each module has a oxygenation/cooling subsystem which supplies oxygen to cathide and air for refrigerate the stack. 8- Each module has a hydrogen subsystem wich is the responsible for hydrogen delivery to stack at ambient pressure. 9- The hydrogen subsystem include a hydrogen purge line. 10- The Electric Power Generation System includes a simulator to reproduce the performance ogf the whole subsystem.
University of Huelva posted this:Procedure for obtaining a renewable resource of metals from acid minewater, and the respective systemsIs known in the state of the art the recovery of metals from the acid aqueous solution that contain them, generally by liquid-liquid extractions. For metals recovery at industrial scale is necessary that these metals can be recovered simultaneously by means of a single extraction step. There are several extraction reagent for this purpose, all these reagent are very expensive and the industrial process for the metal recovery (particularly for rare earth and yttrium) are very complex and finally expensive. The present procedure allows to recovery selectively metals (particularly rare earths and yttrium) by the neutralization of acid mine waters. The objective is to revalue the metal content dissolved in this waters.
University of Huelva posted this:New procedure for the genetic transformation of plant cells and kit for carrying out said methodThe strategy for transformation is extremely simple and does not involves subcloning the gene of interest in any vector. The kit is not based on specific promoters or regulatory DNA sequences, thus it can be applied to many different plant species, from unicellular microalgae to higher plant protoplasts. Since the strategy is not based on specific promoter or regulatory DNA sequences, only the marker and the gene of interest sequences are inserted in the microalgal genome, avoiding the introduction of undeserible DNA sequences in the transformant strain. This is very important given the concern that transfer of exogenous DNA through transgenesis causes in the public opinion