Find the latest Innovations, Patents and Knowhow from top scientistsand innovators in Physical Sciences and Exact Sciences, Nanotechnology, Modelling and Optics
UNIVERSIDAD DE ALICANTE posted this:Novel and simple procedure for dispersing graphene derivatives in chemically curable resins.The Laboratory of Adhesion and Adhesives of the University of Alicante and the company Dental Global Training, have developed a new procedure to incorporate efficiently graphene derivatives (nanofibers, nanosheets, nanoparticles) in chemically cured resins by using an in situ polymerization technique. The method is very simple and fast, it provides an excellent dispersion of the graphene derivatives in both the solid components of the resin and in the cured polymer matrix, and is entirely friendly with the environment. The novel method does not require the use of organic solvents nor water, ultrasounds, and high pressure/temperature. The resulting resin composites show excellent mechanical properties, good wear resistance, easy manipulation and increase the insolubility in oral fluids, and therefor they have special interest in applications in odontology, traumatology and non-medical applications too (automobile, construction, civil engineering, aeronautics, space engineering, electronics and optics). It is looking for companies interested in acquiring this technology for its commercial exploitation.
Institute of Chemical Research of Catalonia posted this:Crysforma: services in pharmaceutical solid state developmentCrysforma provides complete scientific support for the discovery, analysis and scale-up of polymorphs, hydrates, amorphous phases, salts and co-crystals of active pharmaceutical ingredients or intermediates. Crysforma has developed its own crystallization screening methodology based on the combination of several crystallization procedures. We use high-throughput crystallization systems controlled by highly skilled scientists to maximize the information drawn from each experiment. Our projects are always carried out in close collaboration with the client, adapted to the customer's needs and under strict confidentiality conditions.
UATEC - Unidade de Transferência de Tecnologia posted this:Lighting device with adjustable white light based on zirconia nanostructuresA group of researchers from a Portuguese university has developed the concept of a lighting device with adjustable white light based on zirconia nanostructures. The invention aims to control the color temperature of white light emission that is different depending on the morphology/dimension of the particles, on the surrounding environment and on excitation power. The advantage of this type of device is based on the high color quality index and the possibility of color temperature control that is relevant to the lighting technologies market. The university is looking for companies that develop this type of solution on an industrial scale. The university is looking for companies that develop this type of solution on an industrial scale for the further joint development of specific applications or technology licensing.
UATEC - Unidade de Transferência de Tecnologia posted this:Optical pressure sensor based on zirconia nanostructuresA group of researchers from a Portuguese university has developed the concept of a gas pressure gauge based on the control of the luminescence from zirconia nanostructures. The invention aims to measure the gas pressure based on the nanoparticles emission that is different depending on the amount of gas molecules surrounding the nanoparticles. Comparing with existing solutions, the advantage of this process, which operate in a pressure range of interest for various market sectors (ex. Food industry), is the absence of electrical contacts. The university is looking for companies that develop this type of solution on an industrial scale for the further joint development of specific applications or technology licensing.
UNIVERSIDAD DE ALICANTE posted this:New process for the manufacture of electrodes from superporous nanostructured carbon materialsSpanish University have developed a process for the manufacture of electrodes from superporous nanostructured carbon materials. The process uses electrospraying technique to deposit a suspension of a carbon material over a collector. This method facilitates processing superporous nanostructured carbon materials due to its high efficiency and less complexities compared to conventional techniques. The electrodes obtained can be used in energy storage or analytical sensors in commercial devices.
Institute of Chemical Research of Catalonia posted this:ERTFlow: flow reaction technologies and process intensificationERTFLOW is a technology development unit from the Institute of Chemical Research of Catalonia (ICIQ), generated by the know-how produced by the research group of Prof. Miquel Pericàs, to develop and implement technical solutions in process intensification. Our goal is to develop propietary technologies related to catalysis and flow chemistry and offering products and services to the fine chemical, pharmaceutical and biotechnological industries for the production of new products with high added value and guide them in the paradigm change from batch to flow.
Technology Transfer Office
RAMOT at Tel Aviv University Ltd. posted this:Harnessing inhibitory RNA based- nanoparticles for therapeutic intervention in blood cancersModulating T cells functions by down regulating specific genes using RNA interference (RNAi) holds tremendous potential in advancing targeted therapies in many immune related disorders including cancer, inflammation, autoimmunity and viral infections. Hematopoietic cells, in general, and primary T lymphocytes, in particular, are notoriously hard to transfect with small interfering RNAs (siRNAs). Herein, we describe a novel strategy to specifically deliver siRNAs to murine CD4+ T cells using targeted lipid nanoparticles (tLNPs). To increase the efficacy of siRNA delivery, these tLNPs have been formulated with several lipids designed to improve the stability and efficacy of siRNA delivery. The tLNPs were surface functionalized with anti-CD4 monoclonal antibody (mAb) to permit delivery of the siRNAs specifically to CD4+ T lymphocytes. Ex vivo, tLNPs demonstrated specificity by targeting only primary CD4+ T lymphocytes and no other cell types. Systemic intravenous administration of these particles led to efficient binding and uptake into CD4+ T lymphocytes in several anatomical sites including the spleen, inguinal lymph nodes, blood and the bone marrow. Silencing by tLNPs occur in a subset of circulating and resting CD4+ T lymphocytes. Interestingly, we show that tLNPs internalization and not endosome escape is a fundamental event that takes place as early as one hour after systemic administration that determine tLNPs efficacy. Taken together, these results suggest that tLNPs may open new avenues for the manipulation of T cell functionality and may help to establish RNAi as a therapeutic modality in leukocyte-associated diseases. Project ID : 10-2016-962
Universidad de Alcalá-OTRI posted this:New organo-metallic catalysts for the manufacture of polymersA research group from the Inorganic Chemistry Department of Alcalá University has developed a technology that presents a range of catalysts based on coordination complexes and organometallic, active in functionalization processes (expoditation, hydrosilylation) and polymerization of different organic substrates (olefins and cyclic esters). They are metal complexes belonging to the first transition groups (groups 4-6) and elements from the main groups (groups 1,2 and 13). Its application is aimed at the synthesis of materials with new properties (silicon polymers, biodegradable plastics, polyesters) and the production of small molecules with high added value, used as starting products in many industrial processes (epoxides, silanes). The group is looking for manufacturing agreements and joint venture agreements with companies from the agrofood industry, construction and petrochemicals.
Centre Technology Transfer CITTRU posted this:Nanocapsules for delivery of lipophilic compounds and method of their preparationThe present invention provides novel biocompatible “core-shell” systems and the surfactant-free method of their preparation using macromolecular compounds. Biocompatible nanocapsules with liquid cores which enable effective encapsulation of hydrophobic compounds are stabilized without low molecular weight surfactants. These beneficial features significantly increase the range of possible applications.
UNIVERSIDAD DE ALICANTE posted this:Solid-state laser with COPV as active compoundThe research group “Physics of condensed matter” of the University of Alicante has developed a new solid state laser (OSL) where the active compound comprises carbon-bridged oligo(p-phenylenevinylene) (COPV). The main advantages of this technology are photostability, miscibility, processable in thin layers and effective for laser generation at different wavelengths. It can be used in the following industrial sectors: Spectroscopy, biosensors, chemical sensors and optical communications. The research group is looking for companies interested in acquiring this invention or adapting it to their requirements.
UNIVERSIDAD DE ALICANTE posted this:Multicapillary nebulizer for simultaneous nebulization of two or more liquids A Spanish university research group has developed a new pneumatic multicapillary nebulizer which allows the simultaneous nebulization of two or more liquids, miscible or immiscible between them. This device offers the possibility of simplifying the analysis process, reducing the consumption of resources and a high mixing efficiency is achieved. A laboratory-constructed prototype is available for any demonstration. The research group is looking for companies interested in license agreement.
Centre Technology Transfer CITTRU posted this:Method of isolation and purification of xanthophylls from diatom cultureXanthophylls, with their antioxidant, anticancer, anti-inflammatory and neuroprotective properties, found important applications in food and nutrition, cosmetic and environmental industries, as well as pharmacy and medicine. Diadinoxanthin (Ddx) and diatoxanthin (Dtx) are two pigments that belong to xanthophylls family. The availability of Ddx and Dtx on the market is low and up to date limited as they are sold exclusively in small quantities at extremely high prices to be used as HPLC calibration standards. The solution of the above mentioned problems is the 5-step method for the isolation and purification of Ddx and Dtx developed at the Jagiellonian University..
UNIVERSIDAD DE ALICANTE posted this:Innovative procedure for the preparation of silica fillings without shrinkageThe research group Carbon Materials and Environment of the University of Alicante has developed a procedure to prepare silica fillings preventing their shrinkage by the deposition of a thin film prior to the synthesis of the filling. Modifying the said thin film, the filling properties are modified, obtaining highly satisfactory results in the case of the mesoporous thin films in all case studies. This method also allows obtaining silica fillings with different diameters and their incorporation into different types of supports such as glass, steel or honeycombing cordierite monoliths. Following this procedure the shrinkage of the fillings is avoided, which is a common occurrence with the established preparation protocols.
Fundació URV posted this:NEW PROCEDURE FOR OBTAINING MONOLAYERS OF FUNCTIONALIZED NANOPARTICLESThis new procedure (not described in the bibliography) allows the manufacture of monolayers of metal nanoparticles linked by molecules of organic compounds. As you can see in Specifications, this procedure consists in two successive processes. One of the main advantages of this technology is the minimization of impurities in the functionalized monolayer compared to commonly used techniques. Besides, the manufacture of Schotty diode with this new procedure has been shown for the first time. In the same line, this procedure allows the use of monolayers of metal nanoparticles for metabolite detection. These are two unique and differents aspects of this technology in relation to other known used techniques.
Universidad de Alcalá-OTRI posted this:Disposable electrodes based on filtered nanomaterials.A Spanish research Group from Analytical Chemistry, Physical Chemistry and Chemical Departments at University of Alcalá (Spain) has designed and developed different disposable electrodes constituted exclusively by conducted nanomaterials for analytical measurement of electroactive molecules for (bio-) sensoric in relevant areas such as health, agri-food and environmental. The group is looking for companies in the chemistry, clinical, agri-food and environmental sectors to reach licensing agreements or collaboration and commercial agreements for technical assistance.