Universidad de Alicante posted this:Noble metal-free ceria-based diesel soot combustion catalyst, suitable for gas purification in Diesel engine exhaustsThe developed catalyst does not use Pt, which leads to a cheaper product. The resulting catalyst shows equal or even better performance as Pt catalysts. Following the patented procedure of synthesis, the catalyst produced has a lower particle size. This leads to higher surface per particle and therefore, a better ratio yield when interacting in oxidation reactions, leading to a higher oxygen production rate.
Centre Technology Transfer CITTRU posted this:The new oxide catalysts for the removal of nitrogen oxides originating from stationary emission sources.The experiments carried out with the assistance of these catalysts showed a high conversion efficiency of nitric oxide to nitrogen at relatively low temperatures – up to 100%. Designed reactor allows the direct removal of nitric oxide from the exhaust gases via the efficient decomposition of nitric oxide and, at the same time, systematic removal of carbon particles and other solid particles.
uacoopera posted this:Planar diamond thermistors for harsh environments: applied to temperature measurements in combustion and jet engines for the automobile and aerospace industry, lasers, fuel cells and in biological and aggressive chemical environmentsThe new diamond thermistors can be used for temperature measurements in harsh environments such as aggressive chemicals at high temperature or in biological media due to their inertness. Furthermore, the sintered ceramic substrate guarantees superior adhesion and resistance to fracture under high mechanical loads. The fabricated temperature sensitive diamond surface comprises well adhered ohmic contacts deposited on the backside of the dielectric ceramic substrate. This configuration prevents interaction between the temperature sensitive surface and the surrounding environment which is essential for biochemical devices applications. Furthermore, the planar geometry of the disclosed thermistor maximizes the contact region between the temperature sensitive surface and any solid flat surface on which it is placed. In this way, improved response times are obtained comparing to traditional round shaped thermistors.
Universidad de Alicante posted this:“No-Noble-Metal” Catalytic trap to remove Hydrocarbons, NOx and CO emissions from combustion enginesBasically, the catalytic trap bed is composed of a zeolite with a Si/Al ratio between 10 and 20. The zeolite is partially interchanged with cations of one or several non-noble metals. In order to achieve an optimum performance of the catalytic trap, these metals should be interchanged in the internal zeolite structure, and never on its external surface. In this way, the outflow of the exhaust gases passes through the catalytic trap bed to adsorb the HC at low temperatures. The material has been developed at laboratory scale. Different compositions of this material have been tested with simulated streams of internal combustion engines (cold starts). As a result, the material is able to reduce HC emissions in internal combustion engines operating with both mixtures almost stoichiometric and low fuel mixtures. The main difference between this invention and other existing materials is that this catalytic trap avoids any element or additional layer composed of an oxidation catalyst based on noble metals. Consequently, HC emissions could be totally removed through a single bed without using high-cost materials (noble metals) or further stream treatments. This fact allows the catalytic trap to be placed in any position according to the different control systems employed for decreasing other pollutant emissions existing in the gases stream, since the total elimination of HC takes place on the catalytic trap. Thus, this technology development results in a solid material where coexists metal(s) and protons in an optimum ratio inside of the zeolite channels, leading to a system that can act as a HC trap and as an oxidation catalyst in only a single bed, during the whole cold start cycle. The main innovative aspect of this catalytic trap is that the adsorbent material can capture the hydrocarbons in the cold start of the engine and oxidize gases during its warmed-up operating conditions without using noble metals, which are frequently used as oxidation catalyst. At high temperatures, this material is able to carry out total oxidation of both hydrocarbons retained by the catalytic trap and those present in the exhaust gas stream. Consequently, the resulting gas stream released to the atmosphere is innocuous in hydrocarbons. • Noble metals are not used. • Structural advantages, since the control systems are simplified and pollutants in internal combustion engines are reduced. • Economic benefits (The price of noble metal is approximately 100 times more expensive than the materials employed by the researchers). • The catalytic trap can be placed in any position with regard to different control systems. • Besides its hydrocarbon trapping role, the system can also act as oxidation catalyst during the cold-start cycle.
Carlos Barrera posted this:
RAMOT at Tel Aviv University Ltd. posted this:Energy Conversion and TransmissionPower electronics, including high efficiency conversion, photovoltaic systems, and piezoelectric sensors and transmitters enabling energy transmission to human tissue via, for example, implanted medical devices. Project ID : 12-2011-233
RAMOT at Tel Aviv University Ltd. posted this:Hemostatic Soft Tissue AdhesivesNovel bio-adhesives based on the natural polymers, gelatin (protein) and alginate (polysaccharide), and a carbodiimide crosslinking agent. The carbodiimide crosslinking agent is much less toxic than other crosslinking agents used in bioadhesives and therefore our bioadhesives exhibit enhanced biocompatibility. Our bioadhesives provide rapid adhesion, maintain a strong and close apposition of wound edges (to allow for natural wound healing), do not interfere with the body’s natural healing mechanisms and degrade without producing any inflammatory response. In addition, they are viscous liquids before curing, allowing for easy application, and solidify quickly with a low gelation time. Project ID : 2-2011-275
RAMOT at Tel Aviv University Ltd. posted this:Optimization of Myocardial Tissue Repair and Regeneration with Iron-oxide Nanoparticles Formulated in Macrophage-Targeted CarriersMyocardial infarction and the subsequent development of heart failure remains one of the leading causes of morbidity and mortality in the western world. One major new direction for treatment involves optimizing infarct healing and reducing infarct expansion, by controlling early and late inflammation after myocardial infarction and heart failure. Said control implemented through specific manipulations of macrophages - pivotal cells in the onset and progression of inflammation. We are developing a novel conceptual approach, supported by encouraging preliminary data. This approach combines: (i) the application of novel therapeutic agents – iron oxide nano particles and (ii) their selective delivery to macrophages (the target cells) by enclosing these nano particles within special macrophage-targeted carriers. Project ID : 2-2011-272
RAMOT at Tel Aviv University Ltd. posted this:Laboratory of Environmental Bioengineeringenergy efficiency, energy savings, process development Carbohydrate analysis, amino acid analysis. Fermentation processes development Non-thermal extraction on biomolecules process development Non-thermal food and pharmaceutical disinfection with pulsed electric fields Dionex ICS-5000 + Reagent-Free HPIC System for Carbohydrates, Organic Acid and Amino Acid Analysis. Tecan 200M spectrophotometer with gas modules for microfermentation Project ID : 12-2015-918
RAMOT at Tel Aviv University Ltd. posted this:Targeting bone neoplasms and other cancers with novel combined anticancer and anti-angiogenic polymer therapeuticsA new platform technology for the treatment of cancer and bone metastases was developed using combined targeted polymeric drug delivery system with chemotherapeutics and angiogenesis inhibitors. The novel compounds are composed of three main elements: 1.Water-soluble synthetic copolymer such as HPMA (N-(2-hydroxypropyl)methacrylamide) or PGA (polyglutamic acid) as specific carrier enabling the molecules to extravasate from the tumor leaky vessels and internalize into the tumor endothelial and epithelial cells. 2. Specific targeting moieties - Bisphosphanates such as alendronate (ALN) for bone metastases and osteosarcomas or RGD peptidomimetics targeting integrins overexpressed in various tumors. 3. Specific angiogenesis inhibitors, such as TNP-470, a low molecular weight analogue of Fumagilin, that was demonstrated as a selective inhibitor of angiogenesis, or known chemotherapy agents such as Paclitaxel (PTX), that were demonstrated as inhibitors of angiogenesis when given at an "anti-angiogenic dosing schedule" (administration of chemotherapy at low doses, well below the maximum tolerated dose, in close intervals for extended periods of time – “metronomic dosing”). Project ID : 10-2008-86
RAMOT at Tel Aviv University Ltd. posted this:A photocatalytic nanobiocompex composed of integrin-binding, titanium dioxide associated DLDH (RGD¬2-DLDH-TiO2) as a "neo-radiation" targeted treatment for cervical cancerCervical cancer is the second most common malignancy in women with over half a million cases occurring worldwide each year. Despite multi-modal approaches, this disease remains highly resistant and novel approaches for treatment are urgently needed. The cytotoxic effect of photo-excited titanium dioxide (TiO2) by far UV (254 nm) illumination, creating reactive oxygen species (ROS), has been examined in several cancer models in vitro. However, serious damage to the surround healthy cells limits the applicability of this approach. Thus, developing a technique that will achieve TiO2 photoxidative effect at the visible or near UV (>300 nm) range, causing less damage to the healthy is preferred. Our group has recently discovered a unique protein that binds strongly TiO2. This protein, dihydrolipoamide dehydrogenase (DLDH) is critical for energy and redox balance in the cell. Illumination of DLDH, independently, results in elevated levels of ROS. In addition, bioinformatics analysis has suggested that DLDH is a homologue of AIF (Apoptosis-inducing factor), a central player in apoptosis. Cervical cancer cells overexpress the cell surface receptor ?v?3 integrin, which interacts with proteins of the extra cellular matrix through an RGD (Arg-Gly-Asp) recognition site. We bio-engineered the human DLDH with RGD tails (RGD2-DLDH) and generated a protein capable of serving as a bridge between the integrin expressing cancer cell and the TiO2 in its natural and nanostructure forms. We propose that illumination of this complex (RGD2-DLDH-TiO2) will produce high ROS activity and cancer cell death and may serve as a "neo-radiation" targeted treatment in cervical cancer. We believe that the understanding gained from this work will be relevant to other integrin-expressing tumor models that have not been tested so far. Project ID : 8-2014-758
RAMOT at Tel Aviv University Ltd. posted this:Metal alloy nano-foams as Catalysts for Methane Dry Reforming during GTLProof of concept of metal foams as promissing GTL catalyst materials - Electrodeposited Ni-foam catalyst shown stable performance for methane reforming with an area of ca. 5 m2/g, which matches the performance of many supported powder catalysts having areas of 5-20 times larger (Colton Nadal). Advanced development (MF) of high surface-area metal alloy nano-foams as GTL catalysts targets conversion rate of 80% and volume processing of 100 liter/ gram/ hour at atmospheric pressure and 700-800C. Project ID : 6-2015-911
RAMOT at Tel Aviv University Ltd. posted this:Enhancement of Durability, Sensitivity and Selectivity of Environmental Sensors & BioSensors by Peptide NanotubesA Peptide NanoForest, is a dense array of self assembling organic nanotubes, capable of enhancing sensitivity and selectivity parameters of amperometric electrode high-performance sensors. The patented Diphenylalanine (FF) aromatic dipeptide nanotubes are formed under mild conditions from inexpensive building blocks. These bioinspired materials have a unique mechanical strength. They have a high Young’s modulus of about 20–30 GPa. In addition, the inherent biocompatibility of the structures along with the options of their chemical and biological modifications, extraordinary thermal stability, and organic solvent stability, lead to a novel class of nanostructures for sensing applications. The vertical arrangement of the peptide nanotubes enable the deposition of a larger number of nanotubes on the same surface, resulting in a remarkable surface area increase. FF peptide-nanotube-based sensors are benchmarked to CNT-based sensor, and clearly demonstrate the enhancement effect. Project ID : 3-2011-149
RAMOT at Tel Aviv University Ltd. posted this:Characterization of Porous Media for Petroleum ExcavationsA diffusion magnetic resonance (MR) method for non-invasively visualizing geochemistry and microstructures of porous sediment samples. The method provides quantification of pore sizes, pore size distribution and measure on pore eccentricities even for heterogeneous samples in the presence of free water or other liquids. Most diffusion MR methods use single pulsed-field-gradient (PFG) MR sequences; however such sequences are only beneficial for measurement of uniform, highly ordered media. We use the angular bipolar double-pulsed-field gradient (bp-d-PFG) to measure the poly dispersed sizes and shapes of pores of sedimentary rock samples with inter connections and three-dimensional organization. No a priori knowledge on the sizes or distribution is required. Project ID : 6-2012-372
RAMOT at Tel Aviv University Ltd. posted this:Iron oxide nanoparticles (IOP) for the treatment of acute myocardial infarction (AMI) and other inflammatory conditionsA novel approach for the treatment of AMI has been developed using IOPs. IOPs, when injected into the infarcted myocardium, lead to improved heart function after MI. IOPs activate anti-inflammatory macrophages and thus promote tissue healing and repair and prevent myocardial remodeling and dysfunction. Potential Applications IOPs can be used to treat AMI and other inflammatory conditions associated with pro-inflammatory activated macrophages and to promote tissue healing and repair. Advantages ? IOPs are nontoxic ? IOPs are FDA approved for use in humans for MRI imaging Stage In vivo studies in mouse and rat models of MI and heart failure Project ID : 10-2011-247