Deciphering the Virus-Host Tango: Understanding network of interactions through evolution, structure, dynamics, and computational design
Their title: Deciphering the Virus-Tango: Project ID : 47-2020-10875
Summary of the technology
Their title: Deciphering the Virus-Tango:
Project ID : 47-2020-10875
Description of the technology
We compare the interaction between the human ACE2 receptor and the SARS-CoV-2 spike protein with that of other pathogenic coronaviruses using molecular dynamics simulations.
Molecular dynamics simulations reveal a temporal dimension of coronaviruses interactions with the host receptor. The main highlights are:
Using our methodology, we will identify and classify protein-protein interactions, understand the sub-steps in viral infection mechanism, and suggest the most successful therapeutic strategies.
VP Business Development Healthcare
HUJI, Faculty of Science
The Alexander Silberman Institute for Life Sciences
HUJI, School of Computer Science and Engineering
Technology Transfer Office from IsraelYissum - Research Development Company of the Hebrew University
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Founded in 1964 to protect and commercialize the Hebrew University’s intellectual property. Ranked among the top technology transfer companies, Yissum has registered over 8,900 patents covering 2,500 inventions; has licensed out 800 technologies and has spun-off 90 companies. Products that are based on Hebrew University technologies and were commercialized by Yissum generate today over $2 Billion in annual sales.