Yissum - Research Development Company of the Hebrew University

Self-Operated App for Classifform-control ication, Diagnosis, and Rehabilitation of Language Disorders (Aphasia)

Posted by Yissum - Research Development Company of the Hebrew UniversityResponsive · Innovative Products and Technologies · Israel

Summary of the technology

Self-Operated App for Classification, Diagnosis, and Rehabilitation of Language Disorders (Aphasia)
Project ID : 19-2019-6710

Yissum - Research Development Company of the Hebrew University


Life science, Biotechnology


Aphasia, Language comprehension disorder, Rehabilitation, Stroke, Augmentative Alternative Communication (AAC)

Current development stage

TRL7System prototype demonstration; In clinical setting


  • Aphasia is an impairment of language, affecting speech and comprehension of speech and the ability to read and write and is the result of damage to the brain, most commonly from stroke (could also occur due to head trauma, brain tumors or infections).
  • 21%-28% of stroke patients will suffer from aphasia which is associated with higher mortality, morbidity, and utilization of healthcare resources.
  • Low-intensity treatments of aphasia (2-3 hours/week, for 8 weeks) results in little improvement while high-intensity treatment (8-9 hours/week, for 11 weeks) results in significant effects. That, together with the impracticality of supporting that increase in therapist time requires a simple to use, self-treatment tool.

Our Innovation

The research group developed a tablet-based, patient-operated device offering dynamic diagnosis and therapy of language comprehension disorders. The tool evaluates and classifies type and severity of language impairment and generates a treatment plan through an iterative process.

The Advantages

  • Automatic and self-operated, at the home setting.
  • Therapy is evidence-based.
  • Therapy evolves based on the patient’s progress and is personalized.
  • Modular – simple to add new modules and Languages to support additional settings.
  • Well-founded on science and know-how accumulated over years of research in linguistics and neuroscience.

Fig. 1:Tablet Mounted Self-Operated App


The technology addresses a large market:

  • ~1M Aphasia sufferers in the US alone, at any given time
  • Cost, per patient, attributable specifically to Aphasia, in post-stroke patients, is estimated at $2,000
  • The technology taps this market by addressing the gap in the health system’s ability to provide the required treatment for patients with language comprehension disorders and by facilitating the rehabilitation of these patients.

Project manager

Mel Larrosa
VP Business Development Healthcare

Project researchers

Yosef Grodzinsky
HUJI, Faculty of Humanities
Cognitive Sciences

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About Yissum - Research Development Company of the Hebrew University

Technology Transfer Office from Israel

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Founded in 1964 to protect and commercialize the Hebrew University’s intellectual property. Ranked among the top technology transfer companies, Yissum has registered over 8,900 patents covering 2,500 inventions; has licensed out 800 technologies and has spun-off 90 companies. Products that are based on Hebrew University technologies and were commercialized by Yissum generate today over $2 Billion in annual sales.

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