Summary of the technology
Mutant Mycobacterium marinum bacteria as a vaccine against Mycobacteriosis in fish
Project ID : 24-2018-4681
Description of the technology
- M. marinum is a major causative agent of fish Mycobacteriosis, a common bacterial disease in many species of freshwater, brackish water and salt water fish - specifically harming food fish such as Sea Bass, H. S. Bass and Sea Bream, reared under intensive conditions.
- M. marinum bacteria has several isolates, some are potentially zoonotic specifically harmful for marine and aquarium workers.
- M. marinum bacteria harms zebrafish- a commonly used research model, and is considered a major problem in research facilities.
- Today there is no effective vaccine against M. marinum bacteria. In addition, there are no prescribed medications against this bacteria.
A new Mycobacterium marinum (M. marinum ) bacteria-based vaccine can be used as aneffective vaccine against the Mycobacteriosis disease in fish.
- Worldwide problem with a large market.
- M. marinum bacteria harms zebrafish, and is considered a major problem in research facilities.
- Sea Bass is one of thefood fishharmed by M. marinum. In Israel for example, the high incidence of M. marinum, caused the fish growers to stop growing this species