Bi-Functional Coating for the Prevention of the Infection of Dental Implants
Self-assembly of fluorine-capped moieties for prevention of biofilms Keywords: self-assembly, dental, dentistry, biolfilm, disruption Project ID : 9-2015-3142
Summary of the technology
Self-assembly of fluorine-capped moieties for prevention of biofilms
Keywords: self-assembly, dental, dentistry, biolfilm, disruption
Project ID : 9-2015-3142
Description of the technology
Life Sciences and Biotechnology, Chemistry & Materials
Dental, Implants, Infection, Biofilm
Current development stage
TRL3 - Hypothesis testing and initial POC is demonstrated in limited number of in-vitro models
This invention consists of novel and highly improved antifouling materials which spontaneously self-assemble into films and thus promote or encourage adherence of cells.
The physical, chemical and biochemical properties of implant surfaces are some of the most important issues in the design of biomedical devices, as the first interaction between the implant and the body occurs at the interface.
In the case of bacteria, biofouling leads to the formation of a well-defined bacterial network - biofilm. Biofilm formation on medical devices and implants leads to severe infection which may result in patient death.
The materials of the invention are capable of attracting cells from multicellular organisms and preventing antifouling by unicellular organisms. The materials of the invention can be used in biotechnological processes with any eukaryotic cells including mammalian cells or plant cells.
The invention provides a method for preventing, ameliorating, or treating a disease or disorder related to an implant having been placed in a body cavity or on a tissue. The invention provides a method for prolonging the lifetime of an implant and for stimulating or encouraging bone healing or absorption of an implant after implantation.