AQUATIC PLATFORM - Luxembourg Centre for Systems Biomedicine

Summary of the technology

The LCSB Aquatic Platform is centred around the use of zebrafish (Danio rerio), a vertebrate model with high genetic and physiologic similarity to humans. This versatile, reliable model organism is widely used for the in vivo study of developmental biology, gene function, drug discovery and pathophysiological aspects of various human diseases such as epilepsy, rare diseases, neurodegenerative disorders, among others.

University of Luxembourg

Details of the Technology Offer

Our facility consists of a modern semi-automated installation equipped with cutting-edge technology, which allows us to generate genetic disease models (e.g. by CRISPR/Cas9 mutagenesis) and pharmacological models (e.g. by incubation with chemical compounds), as well as to design customized services depending on the user needs.

The LCSB Aquatic Facility can house up to 30.000 adult zebrafish. By maintaining constant micro-environmental conditions, zebrafish are meticulously monitored in order to ensure excellent settings for research quality and animal welfare.

With highly specialized research capabilities and innovative solutions, our team is well-prepared to serve academic, as well as industrial partners, and to contribute to the development of their projects.

SERVICES OFFERED

  • Husbandry practices
  • Embryonic and larval toxicity assays and in vivo drug concentration tests
  • Embryonic and larval screening services
  • Genome editing services
  • Other techniques and services:Tissue isolation/dissections; Counselling for project applications for animal experimentation

CONTACT

LCSB-aquatics@uni.lu

Related Keywords

  • Biological Sciences
  • Biology / Biotechnology
  • Toxicology Technology
  • Genome Research
  • Gene Expression, Proteom Research Technology
  • Genetic Engineering / Molecular Biology

About University of Luxembourg

The University of Luxembourg, founded in 2003, is a European research university with a distinctly international, multilingual and interdisciplinary character. It is a modern institution with a personal atmosphere, close to European institutions, innovative companies and the financial place.

With nearly 6,200 students and about 1,700 employees from all over the globe, the University offers a unique mix of international excellence and national relevance, delivering knowledge for society and businesses. The University has three faculties and three interdisciplinary centers:

• The Faculty of Science, Technology and Communication (FSTC)
• The Faculty of Law, Economics and Finance (FDEF)
• The Faculty of Language and Literature, Humanities, Arts and Education (FLSHASE)
• The Interdisciplinary Centre for Security, Reliability and Trust (SnT)
• The Luxembourg Centre for Systems Biomedicine (LCSB)
• Luxembourg Centre for Contemporary and Digital History (C²DH)

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