Yissum - Research Development Company of the Hebrew University

Hand Held MRI Device for Local MRI Measurements

Posted by Yissum - Research Development Company of the Hebrew UniversityResponsive · Innovative Products and Technologies · Israel

Summary of the technology

alternative method for measuring MRI signals, using NV defects in diamond
Project ID : 6-2017-4449

Description of the technology


Diamond, defects, MRI, nitrogen-vacancy

Current development stage

TRL3 - Hypothesis testing and initial POC is demonstrated


  • The standard MRI approach requires large magnetic fields, yielding bulky and expensive machines. Moreover, the inductive measurement is limited in terms of sensitivity and resolution.
  • These downsides result in limited availability of MRI machines, as well as poor applicability for analyzing small objects (e.g. ovarian status in IVF, gastrointestinal ESD specimens).

Our Innovation

  • A novel method for measuring MRI signals that relies on a different modality of magnetic sensing:
  • High-sensitivity due to the sensor’s proximity to the measured sample, together with an optical readout of the signal, provides orders-of-magnitude higher sensitivity.
  • High-resolution – the optical readout of the MR signal allows high-spatial resolution, down to several 10’s of microns.
  • Small package – the sensor modality consists of a measurement head of mm-scale, which is therefore portable and cheap, and could be integrated into endoscopic configurations.


  • The development addresses medical diagnostic scenarios for currently inaccessible applications
  • Hand held MRI has potential to become a portable device with high availability.
  • The development serves for further research of miniature nuclear magnetic resonance (NMR)

Project manager

Matt Zarek

Project researchers

Nir Bar-Gill
HUJI, Faculty of Science
Applied Physics Department

Related keywords

  • Medicine, Human Health
  • Biology / Biotechnology
  • Genome Research
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  • Recombinant DNA
  • Monoclonal Antibodies and Hybridomas
  • Gene Splicing and Manufacturing Equipment
  • Other Genetic Engineering
  • Molecular design Market
  • Microbiology Market
  • Micro- and Nanotechnology related to Biological sciences
  • Biochemistry / Biophysics Market
  • Toxicology Market
  • In vitro Testing, Trials Market
  • Stem cells and biobanks
  • Cellular and Molecular Biology Market
  • Population genetics Market
  • Gene Expression, Proteom Research Market
  • Bioinformatics Market
  • Enzymology/Protein Engineering/Fermentation
  • Genetic Engineering Market
  • Diagnostic
  • Therapeutic
  • Other Medical/Health Related
  • Agro and Marine biotech
  • Anatomy, Pathology, Immunology, Physiology
  • Clinical Medicine
  • Life Science & Biotechnology
  • medical imaging

About Yissum - Research Development Company of the Hebrew University

Technology Transfer Office from Israel

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Founded in 1964 to protect and commercialize the Hebrew University’s intellectual property. Ranked among the top technology transfer companies, Yissum has registered over 8,900 patents covering 2,500 inventions; has licensed out 800 technologies and has spun-off 90 companies. Products that are based on Hebrew University technologies and were commercialized by Yissum generate today over $2 Billion in annual sales.

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