The human serotonin receptor 5-HT1B is a G protein-coupled receptor. 5-HT1B receptors are present in many parts of the central nervous system, but most notably, can be found in the basal ganglia, striatum, and frontal cortex.
The human serotonin receptor 5-HT1B is a G protein-coupled receptor. 5-HT1B receptors are present in many parts of the central nervous system, but most notably, can be found in the basal ganglia, striatum, and frontal cortex. 5-HT1B receptors inhibit the release of many neurotransmitters, such as serotonin, GABA, acetylcholine, and glutamate. 5-HT1B ligands may prove to be therapeutic in the treatment of various disorders such as depression, anxiety, and aggression.
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