Fundació URV

Potentiometric sensor for the quantitative determination of creatinine

Posted by Fundació URVResponsive · Patents for licensing · Spain

Summary of the technology

Potentiometric sensor for the quantitative determination of creatinine in biological fluids and other aqueous media.
By a new ionophore incorporated into a polymeric membrane that allows screening creatinine real samples. The use of said ionophore in the polymer membrane solve the selectivity problem found in other methods.

New and innovative aspects

New type of molecule-specific recognition (ionophore) incorporated in the polymer membrane that allows selective detection of creatinine in kidney samples.

The proposed approach solves the problem of selectivity and specificity of the signal to show other potentiometric techniques.

Main advantages of its use

The main advantages of this sensor allows direct detection of creatinine in biological fluids with minimal sample treatment quickly, simple to operate and build, requires minimal maintenance and allows additionally perform disposable single-use sensors.

Other advantages are the following:

  • Speed
  • Robustness
  • Stability

  • Low cost

  • Simplicity


Wide range of applications as it allows chemical and biochemical analysis of creatinine in different body fluids that offer improved analysis telemedicine attention points and the possibility to monitor health, since creatinine is an important analyte to analyze and control. The sensor characteristics allow it to be developed portable / wearable scale and improve monitoring.

By the use of this sensor, creatinine levels can be measured constantly in people with kidney problems and metabolism functional problems, favoring a more exhaustive control.


Applications for:

  • Chemical and biochemical analysis
  • Telemedicine
  • Point-of-care
  • Health Monitoring
  • Portable Sensor
  • Wearable sensor

Intellectual property status

PCT application.

Current development status

Laboratory prototypes.

Desired business relationship

Patent licensing.


The ownership of this patent is related to the Rovira i Virgili University (URV), to the Institute of Chemical Research of Catalonia (ICIQ) and to the Catalan Institution for Research and Advanced Studies (ICREA).

Related keywords

  • Diagnostics, Diagnosis
  • Heart and blood circulation illnesses
  • Medical Research
  • Medical Technology / Biomedical Engineering
  • Medical Textiles
  • Medical Furniture
  • Medical Biomaterials
  • Human vaccines
  • Biochemistry / Biophysics Technology
  • Micro- and Nanotechnology related to Biological sciences
  • Health information management
  • Remote diagnostics
  • Sensors & Wireless products
  • Safety & systems
  • Sensor Technology related to measurements
  • Diagnostic services
  • Monitoring equipment
  • Electromedical and medical equipment
  • Diagnostic equipment
  • Welfare technologies
  • sensor
  • biosensors
  • creatinine
  • potentiometric sensor
  • calix[4]pyrrole
  • urine
  • serum
  • wereable

About Fundació URV

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