EG30 for the treatment of Alzheimer's disease

Summary of the technology

EG30 for the treatment of Alzheimer's disease
Project ID : 10-2011-274

Details of the Technology Offer

EG-30: clinical phase drug for AMD and Glaucoma

EG-30 – the highlights:

· Excellent safety profile in healthy volunteers and glaucoma patients

Low systemic exposure

No increase in IOP in glaucoma patients treated with EG-30 for 16days (eye drops)

·Extensive safety and efficacy preclinical package:

EG-30 inhibit the formation of amyloid beta oligomers and serve as a cytoprotectant agent

Efficacy in dry AMD and glaucoma animal models

Safety and toxicology including 6 months toxicology studies in rabbits and monkeys

·An FDA approved development path allowing a single confirmatory study for FDA approval of EG-30 for both glaucoma and dry AMD

·New derivatives for Alzheimer treatment

Project manager

Elisha Natan
Director BD

Project researchers

Ehud Gazit
T.A.U Tel Aviv University, Life Sciences
Molecular Microbiology-Biotechnology

Related Keywords

  • Medicine, Human Health
  • Medical Technology / Biomedical Engineering
  • Biology / Biotechnology
  • Cellular and Molecular Biology Technology
  • Microbiology Technology
  • Bioinformatics Technology
  • Micro- and Nanotechnology related to Biological sciences
  • Microbiology Market
  • Micro- and Nanotechnology related to Biological sciences
  • Biochemistry / Biophysics Market
  • Stem cells and biobanks
  • Cellular and Molecular Biology Market
  • Bioinformatics Market
  • Therapeutic
  • Clinical Medicine
  • Life Sciences and Biotechnology
  • small molecules
  • Pharmaceutical Indications
  • cns
  • cns

About RAMOT at Tel Aviv University Ltd.

Ramot is Tel Aviv University's (TAU) technology transfer company and its liaison to industry, bringing promising scientific discoveries made at the university to industry's attention. The company provides the legal and commercial frameworks for inventions made by TAU faculty, students and researchers, protecting discoveries with patents and working jointly with industry to bring scientific innovations to the market.

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