Yissum - Research Development Company of the Hebrew University

Novel Compounds Prevent Biofilm Development on Food Packaging and on Fresh Foods

Posted by Yissum - Research Development Company of the Hebrew UniversityResponsive · Innovative Products and Technologies · Israel

Summary of the technology

Novel Compounds Prevent Biofilm Development on Food Packaging and on Fresh Foods
Project ID : 23-2014-3072

Yissum - Research Development Company of the Hebrew University

Description of the technology

New and innovative aspects

Novel Compounds Prevent Biofilm Development on Food Packaging and on Fresh Foods Project ID : 23-2014-3072

Bacteria in biofilms implicated in food-borne diseases

Categories

Biofilm, Food Packaging, Polymers, Biomaterials, Post Harvest, Fresh Produce

Development Stage

Industrial trials

Patent Status

Patent applications filed in the US (2011-0281921-A1) and Europe (2365969).

Highlights

  • Simple heterocyclic compounds disrupt cell–cell communication (quorum sensing) interfering with the formation of biofilms
  • Compounds added to packaging and shipping crates prevent the formation of biofilm, resulting in cleaner, healthier produce
  • Protect fresh fruits and vegetables being shipped long distances
  • Prolongs shelf life of products

Our Innovation

Novel compounds that disrupt cell–cell communication (quorum sensing) and interfere with the formation of biofilms can be used as coatings on food packaging materials to prevent the formation of biofilms that induce disease-causing fungi and bacteria. (See Newsweek article: http://www.newsweek.com/2014/07/25/spray-keep-bacteria-laden-biofilms-growing-food-259323.html

Left: Treated surface, Right: Untreated control

Red: Dead bacteria, Green: Live bacteria

Key Features

  • Technology successfully incorporated into acrylic polymers used to coat corrugated cardboard used for fresh produce
  • No antibacterial or antifungal effect, avoids development of resistant strains
  • Environmentally safe – non-leaching coating
  • Effective against both fungal and bacterial biofilms
  • Inhibit and reverse biofilm formation

Development Milestones

  • Additional compounds to be synthesized
  • Additional Field trials in agricultural, municipal and industrial water pipes, homes and hospitals

The Opportunity

  • Technology can be applied to washing tanks of fresh fruits and vegetables
  • Technology can be applied to frozen food packaging, poultry and meat packaging, and other areas within the food packaging industry
  • Other applications include industrial water treatment in open and closed water systems, prevention of biofilm formation on filtration membranes, paints and coatings, irrigation pipelines, paper-making machines, fouling of marine vessels

Project manager

Michal LevyVP Head of Bus. Dev. Agri-Tech, Vet. & Environment

Project researchers

Doron SteinbergHUJI, Faculty of Dental MedicineOral Medicine

Related keywords

  • Agriculture
  • Agro chemicals
  • Technologies for the food industry
  • Food quality and safety
  • Micro- and Nanotechnology related to agrofood
  • Agriculture, Forestry, Fishing, Animal Husbandry and Related Products
  • Agricultural genetic engineering applications
  • Agricultural chemicals
  • Food and Beverages
  • agriculture

About Yissum - Research Development Company of the Hebrew University

Technology Transfer Office from Israel

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Founded in 1964 to protect and commercialize the Hebrew University’s intellectual property. Ranked among the top technology transfer companies, Yissum has registered over 8,900 patents covering 2,500 inventions; has licensed out 800 technologies and has spun-off 90 companies. Products that are based on Hebrew University technologies and were commercialized by Yissum generate today over $2 Billion in annual sales.

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