Yissum - Research Development Company of the Hebrew University

A new method for the optimal selection and placement of landmarks for registration in navigated neurosurgery

Posted by Yissum - Research Development Company of the Hebrew UniversityResponsive · Innovative Products and Technologies · Israel

Summary of the technology

A new method for the optimal selection and placement of landmarks for registration in navigated neurosurgery
Project ID : 7-2007-1923

Yissum - Research Development Company of the Hebrew University

Description of the technology

We have invented a novel framework and methods for the optimal selection and placement of anatomical and fiducial landmarks for image-guided neurosurgery. The method computes the rigid registration transformation that minimizes the Target Registration Error, and provides an accurate estimate of the target localization uncertainty. It allows surgeons to optimally plan fiducial location prior to imaging and to automatically or semi-automatically select the fiducial and anatomical landmarks that will minimize the Target Registration Error. The proposed method takes the guesswork out of the registration process, provides a reliable localization uncertainty error for navigation, and reduces the localization error. It is expected to provide a new, principled pre-imaging method for fiducial placement, save intra-operative time, and improve the reliability and accuracy of the localization. Based on our preliminary clinical results, the expected reduction of uncertainty is of up to 4mm. The improvement in accuracy is expected to reduce complications and allow new procedures that could not be done because of the suboptimal localization uncertainty.

A US Provisional application has been submitted.

Project manager

Tamir Huberman
VP Business Dev. Computer Science & IT Director

Project researchers

Leo Joskowicz
HUJI, School of Computer Science and Engineering
CS

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About Yissum - Research Development Company of the Hebrew University

Technology Transfer Office from Israel

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Founded in 1964 to protect and commercialize the Hebrew University’s intellectual property. Ranked among the top technology transfer companies, Yissum has registered over 8,900 patents covering 2,500 inventions; has licensed out 800 technologies and has spun-off 90 companies. Products that are based on Hebrew University technologies and were commercialized by Yissum generate today over $2 Billion in annual sales.

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