Yissum - Research Development Company of the Hebrew University

Tiltan Pharma

Posted by Yissum - Research Development Company of the Hebrew UniversityResponsive · Investment Opportunities in Startups and Spinoffs · Israel

Summary of the technology

Anti-angiogenic drug combination
Project ID : 26-2006-467

Yissum - Research Development Company of the Hebrew University

Description of the technology

Mechanism-Based Anti-Angiogenic Drug-Combination to Treat Cancer

Tiltan Pharma is a start up company that developed a novel treatment for cancer which is now at a phase-II clinical study in metastatic pancreatic cancer. The company has recently completed a round of investment and seeks further funding to accelerate and complete this phase-II

About the company

Tiltan Pharma Ltd, an Israeli company jointly owned by Yissum (Technology transfer Company of the Hebrew University), the entrepreneurs, Israeli investors and a Canadian corporation, is dedicated to the development and commercialization of its proprietary anti-angiogenic platform for treatment of cancer and other indications.

Our product

TL-118 is a proprietary anti-angiogenic therapy aiming to starve the tumor by cutting off its blood supply.

The product represents an innovative approach to use known molecules for this indication, thereby shorten time to market and risks of development.

A recent study conducted by an independent researcher and published in the British Journal of Cancer, showed superiority of TL-118 over current standard of care anti-angiogenic agents:

http://tiltanpharma.com/var/968/3032-bjc2012322a.pdf

Development Milestones

Over 150 cancer patients were exposed to TL-118 so far with excellent safety and tolerability and good signs of efficacy.

The company was granted a US-FDA IND and a recent safety report showed the product is safe and well tolerated.

Tiltan's product, TL-118, is protected by a composition of matter patent already granted in the US, Europe, Canada, Australia, Japan, China and Israel.

The company' next milestone is the completion of its phase-II pancreatic cancer study conducted in parallel in the US and Israel.

Contact details

Dan@TiltanPharma.com

http://tiltanpharma.com/

Project manager

Ariela Markel
VP, Business Development, Healthcare

Project researchers

Shmuel Ben-Sasson
HUJI, Faculty of Medicine
Experimental medicine and cancer research

Related keywords

  • Socio-economic development models, economic aspects
  • Other (uncategorised)
  • Investment Opportunities
  • Life Science & Biotechnology

About Yissum - Research Development Company of the Hebrew University

Technology Transfer Office from Israel

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Founded in 1964 to protect and commercialize the Hebrew University’s intellectual property. Ranked among the top technology transfer companies, Yissum has registered over 8,900 patents covering 2,500 inventions; has licensed out 800 technologies and has spun-off 90 companies. Products that are based on Hebrew University technologies and were commercialized by Yissum generate today over $2 Billion in annual sales.

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