Yissum - Research Development Company of the Hebrew University

Knowhow - A New Tool for the Automatic Classification of all Known Proteins

Posted by Yissum - Research Development Company of the Hebrew UniversityResponsive · Research Services and Capabilities · Israel

Summary of the technology

A novel approach in which the sequence space is viewed as a directed graph. Graph theoretic and algorithmic tools are applied to investigate the properties of sequence space. Using these tools we look for clusters (groups) of related proteins in this space, and verify the correlation of these clusters with high level features of proteins. The results show that clusters correspond to protein families.

Former responsible Tami Kfir
Project ID : 10-2006-300

Yissum - Research Development Company of the Hebrew University

Description of the technology

Available Knowhow

An automatic method of classifying molecules

The present invention relates to an automatic method of classifying molecules having similar biologic function comprising the steps of: a) creating a hierarchical organization of said molecules in a database, wherein groups of clusters are identified using local consideration resulting in related clusters; b) determining the position of a selected molecule based on the hierarchical organization of step a, whereby selected molecules of similar biologic function are classified.

Link to Full Patent Text:

http://goo.gl/v4jLDn

Project manager

Tamir Huberman
VP Business Dev. Computer Science & IT Director

Project researchers

Naftali (Tali) Tishby
HUJI, School of Computer Science and Engineering
CS - Machine Learning

Nathan Linial
HUJI, School of Computer Science and Engineering
CS - Computational Biology

Golan Yona
,

Related keywords

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  • Computer Science & Engineering
  • Available Knowhow
  • computational biology

About Yissum - Research Development Company of the Hebrew University

Technology Transfer Office from Israel

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Founded in 1964 to protect and commercialize the Hebrew University’s intellectual property. Ranked among the top technology transfer companies, Yissum has registered over 8,900 patents covering 2,500 inventions; has licensed out 800 technologies and has spun-off 90 companies. Products that are based on Hebrew University technologies and were commercialized by Yissum generate today over $2 Billion in annual sales.

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