Consejo Superior de Investigaciones Científicas

Consejo Superior de Investigaciones Científicas

Public Agency

Calle Serrano, 117, Madrid, 28006, Spain · Spain | BASIC

About Consejo Superior de Investigaciones Científicas

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The Spanish National Research Council (in Spanish 'Consejo Superior de Investigaciones Científicas (CSIC)') is a government agency for basic and applied scientific research.

It is the largest public research organization in Spain, with presence in all the Autonomous Communities through 126 centers and 145 associated units.
Research areas
Electronics, IT and TelecommsIndustrial manufacturing, Material and Transport TechnologiesIndustrial TechnologiesEnergy TechnologyBiological Sciences and 6 more
Organization Website
Organization Type
Public Agency
Founded
1907
Headquarters
Calle Serrano, 117, Madrid, 28006, Spain

Publications (45)

CSIC has developed a reliable and effective method for obtaining oleuropein from olive leaf: comprising a pretreatment that increases the concentration of oleuropein in the extracts over other known methods and achieving this bioactive compound with a purity superior of 70%. Industrial partners[…]

CSIC has developed a method for the production of nanoporous solids that contain gas inside their pores. The method is based on magnetron sputtering, but gas consumption is lower in comparison with conventional sputtering methods carried out in dynamic regime. Experimentally, layers of controlled […]

CSIC and the University Miguel Hernández have developed a minimal peptide core from the M yti lus galloprovidencialis Myticin C peptide with unique in vitro and in vivo wound healing and regenerating activities. Industrial partners from the pharmaceutical and cosmetic industry are being soug[…]

ppaatthhoollooggiieess CSIC and UAM have developed compounds that positively modulate protein-protein interactions that involve KChIP2 protein. Industrial partners from the pharmaceutical industry are being sought to collaborate through a patent licence agreement An offe[…]

CSIC has developed a chimeric protein that, when expressed in bacteria, changes its structure upon absorption of blue light, thus generating protein aggregates (amyloids) that inhibit bacterial growth Industrial partners from the pharmaceutical industry are being sought to collaborate through a […]

CSIC has developed a methodology to rear the meadow spittlebug Philaenus spumarius (L.) (Hemiptera, Aphrophoridae) in control climatic conditions in the laboratory allowing the supply of nymphs and adults before they become available in the field. This continuous indoor-rearing protocol could fac[…]

CSIC have developed a method for the in vitro generation of antigen-specific antibodies or cells producing thereof by means of the development of an in vitro germinal center useful to produce vaccines, immunomodulators or immunotherapies. Industrial partners from the biotechnology and/or pharmace[…]

CSIC has developed a new system that allows to identify and classify nanometric and micrometric particles. This system is based on the changes produced at different resonance frequencies of thin plate type structures when these particles are adsorbed onto their surface. This technology represents […]

CSIC has developed a sample analyzing system that can identify particles and/or biological cells in aqueous suspension or in physiological medium. The system allows simultaneously measuring the mass and light scattering of the particles in suspension in real time. This technology has been used to […]

CSIC has developed a resistive thermal source suitable for thin layer deposition by Physical Vapor Deposition. Deposition can be optimized with the new sources since they admit more than twice the evaporant mass compared with conventional sources consisting in helical filaments of the same length […]

has developed a device based on nanogenerators for electrical cells stimulation without the need of electrodes or bulky devices. The device is biocompatible and, among its multiple applications, is able to actuate in medical prostheses as enhancer of cellular growth and proliferation, which permit[…]

CSIC have developed a method that allows to generate pulsed signals of high power and energy through control over the spatial distribution of the intensity, nonlinear effects and the dispersive characteristics inside a laser. This method offers interesting possibili[…]

Apricot is a stone fruit species with a long history of cultivation in Spain. Nevertheless, traditional varieties that have served remarkably well in past decades are now struggling to respond to new demands, both relative to cultivation and the market. The spread of the sharka virus (Plum pox virus[…]

CSIC has developed a procedure to extract bioactive compounds from wet biomass, in example microalgae or/and seaweeds, by using a sequential methodology. The procedure is quick, selective, give high yields, maintain bioactivity and minimize the impact to the environment. Industrial partners f[…]

Transphagocytic T cells as anti cancer immunotherapy CSIC´s research group, in collaboration with scientists from the Centre of Molecular Biology “Severo Ochoa” (CBMSO-CSIC), the Autónoma University of Madrid and the Health Research Institute of the “La Princesa” University Hospital, developed a new[…]

CSIC and the University of Würzburg have developed a new method to eliminate antibiotic-resistant bacterial infections using classical antibiotics previously discarded due the occurrence of antibiotic resistance. Industrial partners from the pharmaceutical industry are being sought to collaborate t[…]

CSIC through the Instituto de Microelectrónica de Barcelona - Centro Nacional de Microelectrónica, has developed a device based on nanogenerators for electrical cells stimulation without the need of electrodes or bulky devices. The device is biocompatible and, among its multiple applications, is abl[…]

CSIC has developed a water filtration installation. It contains tanks designed to perform various functions: water filtration by means of ultrafiltration, water filtration by reverse osmosis and recycling of reverse osmosis membranes. This installation is used, for example, in seawater desalination […]

CSIC have developed organic derivatives, low cost, with possibility of modifying its molecular structure, including different substitutions, improving the properties of electronic semiconductor. These molecules present not only interesting electronic properties which make them active[…]

CSIC has synthesized several substituted purine derivatives that are capable of inhibiting the activity of the CDC7 kinase. This inhibitory activity makes them useful for the treatment of neurological diseases. The compounds developed are, therefore, a new therapeutic alternative for Alzheimer's d[…]

CSIC, Carlos III University of Madrid and CIEMAT have repositioned drugs that stimulate endogline expression and modulate the TGF-β route for a new clinical use in the treatment of fibrosis, such as epidermolysis bullosa (EB). EB includes a heterogeneous group of rare hereditary diseases of the skin[…]

Control of neurodegenerative diseases with benzothiazole-benzamide derivatives CSIC has developed a group of heterocyclic compounds derived from a privileged structural nucleus with the capacity to inhibit the LRRK2 enzyme. This inhibitory activity makes them useful in the treatment of neurodegenera[…]

CSIC and Complutense University of Madrid have developed new kits for cell culture based on cytocompatible hydrogels coated onto stiff substrates. Due to the excellent adhesion of the hydrogel to these substrates is possible to have mechanically robust platforms, easy to handle as required in a ce[…]

CSIC and the University of Athens have found that secoiridoids, such as oleacein and oleocanthal, are useful to prevent or treat illnesses that results in immune-mediated gastrointestinal alterations. A company dealing with pharmaceutical or nutraceutical compositions is sought for licensing agreem[…]

CSIC has developed a procedure for the biotechnological production of 11α hydroxylated steroids by generating and subsequent use of recombinant bacteria. These recombinant bacteria allow to perform microbial biotransformation processes that result in 11αhydroxylated steroid compounds from raw materi[…]

CSIC and the University of Athens have found that secoiridoids, such as oleacein and oleocanthal, are useful to prevent or treat neuropathies that conduct to optic nerve injury, such as optic neuritis. A company dealing with pharmaceutical or nutraceutical compositions for ophtalmic applications is[…]

CSIC has developed tips for scanning probe microscopy (SPM) where an isolated nanoparticle is placed at the apex of the tip. The method allows to tailor the shape, size and composition of the nanoparticle improving the measuring capabilities of the tips. These novel tips are suitable for techniques […]

a a l l CSIC, University of Zaragoza and Technische Universität Dresden have developed an enzymatic composition and its use as an enzymatic cascade for the production of 2,5-furandicarboxylic acid (FDCA) from 5-methoxymethylfurfural (MMF). This cascade is self-sustained with the only consumptio[…]

R R α α 2 2 o o v v e e r r e e x x p p r r e e s s s s i i o o n n CSIC has developed a peptide capable of inhibiting the signaling of IL-13 mediated by IL13Rα2. This peptide alone or within a nanoparticle or virus-like particles can be used in a pharmaceutical composition for the treatment of […]

CSIC has synthesized a series of piperidine derivatives that are capable of inhibiting the activity of the enzyme phosphodiesterase-8 (PDE8). This inhibitory activity makes them useful for the treatment of neurodegenerative diseases in which this enzyme is overexpressed. The compounds developed are,[…]

The CSIC and IRYCIS (Ramón y Cajal Institute for Health Research) have developed a group of compounds. These compounds have the ability to regulate the number of synapses that are formed between neurons, as well as the probability that neurotransmitters are released from these, because they have the[…]

CSIC, the University of Zaragoza, Institute Pasteur, IISA and ARAID have developed chemical derivatives that act selectively against the bacterium Helicobacter pylori, managing to reduce the bacterial load and even eradicate gastric infections caused by it. Industrial partners fr[…]

The CSIC and University Pablo de Olavide have developed a system for warning possible failure of the anaerobic digestion process carried out in a digester, using a microbial fuel cell connected to the digester by recirculation. This system is called Previous Destabilization A[…]

CSIC and the Universitat Politècnica de València have developed a method for the detection and quantification of all species of the viral genus Potyvirus present in plant samples. The different species of the genus Potyvirus cause losses of up to 90% of production in crops of high economic interest,[…]

CSIC has developed a process for the enzymatic synthesis of alkyl esters of long chain fatty acids in the presence of an alcohol and an enzymatic preparation with a sterol esterase/lipase covalently immobilized on magnetic particles functionalized on its surface. The process increases the yield of[…]

CSIC and the Center for Research in Agricultural Genomics have developed an effective method for plant tissue regeneration that involves the use of a bacterial cellulose-based biopolymer. The application of this material directly in plant wounds enhances the formation of new cells layers which boost[…]

The Spanish National Research Council (CSIC) have developed a humidity senso r. This sensor allows to detect and quantify the surrounding humidity by optical transduction. The device is based in the optical response of a photonic crystal. This humidity sensor has been successfully tested showing r[…]

CSIC has developed a modulating agent for regulating body weight. Nowadays, it is necessary to develop new alternatives to increase the profitability of animal breeding and increase meat production, key factors to meet the food needs of the world population. Since weight and body fat are two importa[…]

CSIC has developed a material based on a mixture of metal oxides. This new material is capable of releasing oxygen gas during its reduction through an endothermic process and regenerating in air at high temperature (800-1000 ºC) releasing energy. The material behaves in a stable manner in successive[…]

CSIC and UPV have developed a system that allows modulating the degree of silencing of any gene that is of interest in plants. Until now, the technologies used to regulate gene expression in plants only allowed to induce a high degree of silencing, but the level of silencing had not been regulated[…]

CSIC and the University of Oporto have developed a method that combines lithographic printing techniques, aluminium anodizing for the manufacture of highly ordered nanoporous alumina templates and metal sputtering by which metal nanostructures with the same ordering pattern are ob[…]

CSIC has developed a biocatalytic transformation of isophorone (3,5,5-trimethylcyclohex-2-en-1-one) and 4-hydroxyisophorone (4HIP) to selectively produce 4-hydroxyisophorone and 4-ketoisophorone (4KIP), valuable products for pharmaceutical, flavor and fragrance industry. The biocatalysts employed […]

CSIC through the Instituto de Microelectrónica de Barcelona - Centro Nacional de Microelectrónica, has developed a novel JFET (Junction Field-Effect Transistor) which is very suitable to be used in high-radiation-level environments such as Space, high-flying aircraft, particles accelerator or radio-[…]

CSIC through the Instituto de Microelectrónica de Barcelona - Centro Nacional de Microelectrónica, has developed a device based on nanogenerators for electrical cells stimulation without the need of electrodes or bulky devices. The device is biocompatible and, among its multiple applications, is abl[…]

Molecular Method that radically improves the diagnosis of Hereditary hemorrhagic telangiectasia (HHT). The Granada University, Health and Progress Foundation, and the CSIC have developed a diagnostic molecular system for the HHT by getting a simple liquid biopsy from the patient. Industrial partn[…]

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Contact Person

Irene Uceda

Irene Uceda

Employee at Consejo Superior de Investigaciones Científicas

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