Co-crystallization technologies and solid form studies for research and development of active pharmaceutical ingredients.

O-63Enantia / Spain Innovation in Spain : Open opportunities ...
Co-crystallization technologies and solid form studies for research and development of active pharmaceutical ingredients.

Solubility, bioavailability, Cocrystals, Solid form screening, Solid form characterisation

Organization type : SMEs

Type of tech offer : Services

Current Development Status : Finished technologies

Required business relationship : Joint ventures , Technology selling

Industry : Pharmaceutical, Healthcare, Chemical

Domains of Knowledge : Chemistry, Life sciences

Posted on: 07/03/2013 Deadline : 05/10/2013 Active users : 2037 Tech Offer ID : O-63

Description of the technology offer

Determining the appropriate solid form of an active pharmaceutical ingredient or intermediate is a key aspect of drug development. Solid forms can shape the pharmacokinetic and formulation properties of a drug candidate to such an extent that the right solid form can be the key to a successful project. It is therefore strongly recommended to address solid form studies in the early phases, even when the molecule is still in the discovery stage.
Enantia, with a remarkable experience in the field of pharmaceutical cocrystals, offers its particular approach to cocrystal screening (a combination of rational design with intensification technologies) and solid form characterisation.

New and innovative aspects

CO-CRYSTALLlZATION TECHNOLOGIES

The application of co-crystallization technologies has only recently been recognised as a way to improve physico-chemical properties of APIs and their synthetic intermediates. Better profiles may include enhanced solubility, better stability and the extension or widening of IP position with respect to the development of active pharmaceutical ingredients (APIs).

Enantia has developed a strong know-how in terms of identifying suitable count... Read more

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